en Health Education Health Education Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Stigma and a lack of knowledge are significant barriers to seeking mental health support, particularly among adolescents. In Iran, there is a scarcity of interventional studies addressing these issues, and the findings from existing research are often inconsistent. This study translated and culturally adapted the Canadian Guidance about Mental Health and the High School Curriculum for implementation in Iranian schools to address this gap. This study aims to determine the effect of this educational intervention on the mental health literacy of Iranian students. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> This research employed a quasi-experimental design involving a sample of two hundred middle school children aged 14.28 &plusmn; 0.7 years, ranging from 13 to 16 years old. The educational intervention for the experimental group consisted of six sessions, each lasting 45 to 60 minutes. Data were collected using the Knowledge and Attitudes to Mental Health Scales (KAMHS). The data were analyzed using inter-group and intra-group repeated measures ANOVA, with a significance cutoff of </span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"><0.05. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b>&nbsp; There were no significant differences in demographic characteristics between the intervention and control groups. However, the intervention group demonstrated significant improvements in mental health behaviors, a reduction in stigma, and an increase in help-seeking, while the control group showed no such changes (</span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"><0.05). </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion:</b> The designed intervention was effective in increasing knowledge and attitudes.</span></span></span></span></span></span></span></span><br> &nbsp; Mental Health Literacy, Knowledge, Attitude, Mental Health, High School Students 104 113 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-9329-1&slc_lang=en&sid=1 Zahra Saboohi saboohizahra2020@gmail.com 200319475328460096591 200319475328460096591 No Department of Health Services, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Ava Sadat Hoseini avasadat.hoseini@yahoo.com 200319475328460096592 200319475328460096592 No Department of Health, Faculty of Medical Sciences, Karaj Branch, Islamic Azad University, Karaj, Iran Azade Sadat Hoseini A.Hoseini@outlook.com 200319475328460096593 0009-0003-7015-6270 No Department of Psychology, Faculty of Humanistic Science, Urmia Branch, Islamic Azad University, Urmia, Iran Sadegh Ghasemzadeh Rishkani ghasemzadeh.sa@iums.ac.ir 200319475328460096594 200319475328460096594 No Department of Health Services, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Mahnaz Solhi solhi.m@iums.ac.ir 200319475328460096595 200319475328460096595 Yes Air Pollution Research Center, Iran University of Medical Sciences, Tehran, Iran