en Occupational Medicine Occupational Medicine Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b>&nbsp;&nbsp;</b><b><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp; Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Hearing loss (HL), including noise-induced hearing loss (NIHL), is a prevalent health issue that affects millions of individuals worldwide and ranks as the third most common disability. This study examines the relationship between HL and cardiovascular risk factors (RFs) such as hypertension (HTN), diabetes mellitus (DM), and dyslipidemia (DLP) within the Iranian adult population. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> This study was carried out at Iran University of Medical Sciences and involved 1,996 individuals undergoing routine health checks, including audiometry and lab tests. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> The study indicated that older age (per each additional year of age, aOR=1.14, 95%CI: 1.12-1.16, </span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"><0.001) and male gender (aOR=3.08, 95%CI: 1.84-5.14, </span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"><0.001) were significantly associated with HL, while a higher educational level served as a protective factor (tertiary education compared to a primary school degree, aOR=0.35, 95%CI: 0.24-0.5, </span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"><0.01). Although initial analyses suggested associations between HL and cardiovascular RFs, these associations lost significance after adjusting for confounding variables. Notably, the presence of a single cardiovascular RF was significantly linked to HL in the total sample (aOR=1.37, 95%CI: 1.04&ndash;1.81, </span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.02) and in men (aOR=1.41, 95%CI: 1.05&ndash;1.90, </span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.02), but not in women. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion:</b> This research emphasizes the significant association between hearing loss and demographic factors such as age, gender, and educational attainment in Iranian adults. These findings underscore the necessity for inclusive hearing health strategies that take these factors into account in both occupational and public health contexts.</span></span></span></span></span></span></span></span><br> &nbsp; Noise-induced hearing loss, Hearing impairment, Cardiovascular risk factors, Hypertension, Diabetes mellitus, Dyslipidemia, Demographic characteristics, Cross-sectional study, Iranian adults 198 205 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-9410-2&slc_lang=en&sid=1 Mahdi Soheyli mahdisoheyli.ms@gmail.com 200319475328460096875 0009-0002-6543-5075 No Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Mobin Obeidinia mobinobd918@gmail.com 200319475328460096876 200319475328460096876 No Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Arya Shirani shiraniaria@gmail.com 200319475328460096877 200319475328460096877 No School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Lena Nazemi Nazemi.le@iums.ac.ir 200319475328460096878 200319475328460096878 No Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Zahra Rampisheh rampisheh@gmail.com 200319475328460096879 200319475328460096879 No Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Hajar Nikbakht hajarnikbakhtfini@gmail.com 200319475328460096880 200319475328460096880 No Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Mahdi Chinichian chinichian.m@iums.ac.ir 200319475328460096881 200319475328460096881 Yes Department of Occupational Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran Batool Tayefi tayefi.b@iums.ac.ir 200319475328460096882 200319475328460096882 No Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran