Volume 9, Issue 3 (10-1995)                   Med J Islam Repub Iran 1995 | Back to browse issues page

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IN TRAOPERATIVE RADIATION THERAPY FOR GASTRIC ADENOCARCINOMA
B SADEGHl-LOOYEH , FN GILLY , PY CARRY , AC SAYAG , JB GRIOT , P ROMESTAING , I SENTENAC , G BRAILLON , JP GERARD
From the Departments of Digestive Surgery and Radiotherapy, Centre Hospitalier Univesitaire Lyon Sud, 69495, Pierre Benite Cedex, France.
Abstract:   (4995 Views)
Intraoperative radiation therapy (IORT) is a multidisciplinary approach in which residual tumors or tumor beds are directly irradiated during a surgical procedure. To evaluate its efficacy, from 1985, we conducted a prospective study including non-metastatic gastric adenocarcinoma treated by surgery, IORT (15 Grays) and postoperative external beam radiotherapy (44 Grays). Up to 1993, 51 cases of gastric adenocarcinoma (20 pN0 and 31 pN1-2) have been included in the study. Mortality and morbidity rates were not different from those of surgery alone. The overall 5 year survival rate was 59.1 %, and the pN1N2 5 year survival rate was 50.6'70. These promising results are comparable with those of Asian randomized studies which demonstrate the possible value of IORT in the treatment of gastric adenocarcinoma.
Keywords: Gastric adenocarcinoma. Radiotherapy. Intraoperative radiation therapy.
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Type of Study: Original Research | Subject: Surgery
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