Volume 4, Issue 2 (5-1990)                   Med J Islam Repub Iran 1990 | Back to browse issues page

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MAKVANDI M, DIGHE P, KALANTARI H. STUDIES ON HEPATITIS B VACCINES. Med J Islam Repub Iran 1990; 4 (2) :125-128
URL: http://mjiri.iums.ac.ir/article-1-1559-en.html
From the' Department of Microbiology and Immunology, Ahwaz University of Medical Sciences, Ahwaz,
Abstract:   (3224 Views)
HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Green Cross Corporation, Osaka, Japan). We conclude that vaccine prepared by PEG-6000 precipitation gives better results.
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