Volume 29, Issue 1 (1-2015)                   Med J Islam Repub Iran 2015 | Back to browse issues page

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Talachian E, Bidari A, Noorbakhsh S, Tabatabaei A, Salari F. Serum levels of vitamins A and D, and zinc in children with acute diarrhea: A cross-sectional study. Med J Islam Repub Iran 2015; 29 (1) :385-391
URL: http://mjiri.iums.ac.ir/article-1-2884-en.html
Emergency Department, Hazrat-e-RasoulAkram Hospital, Iran University of Medical Sciences, Tehran, Iran. , bidari.a@iums.ac.ir
Abstract:   (4326 Views)

  Background: Diarrhea is a leading cause of mortality and morbidity during the early life period especially in developing countries. Micronutrients deficiencies have been proposed either as a risk factor or a consequence of diarrhea. Association studies highlight the relation of vitamins and minerals’ deficiencies with acute diarrhea. In this regard we aimed to evaluate the status of vitamins A and D, and zinc serum levels in children with acute diarrhea.

  Methods : In this cross sectional study performed in a referral teaching hospital, we measured and compared baseline vitamin A, 25-hydroxy vitamin D (25(OH)D), and zinc serum levels in 25 children admitted with acute diarrhea and 25 other children who were admitted for undergoing elective surgeries.

  Results : 25-(OH)D levels were significantly lower in the diarrhea group (p=0.03). We were unable to demonstrate a significant difference in the levels of vitamin A and zinc between the case and control groups (p= 0.14 and p=0.07, respectively).

  Conclusion : We observed lower serum 25(OH)D levels in children with acute diarrhea. Whether this finding indicates a premorbid risk factor or simply a consequence of diarrhea needs further studies. Regardless of the cause and effect relationship, supplementation with vitamin D in acute diarrhea remains as a plausibleconsideration.

  

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Type of Study: Original Research | Subject: Pediatric

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