Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1377
2
1
gregorian
1998
5
1
12
1
online
1
fulltext
en
EFFECT OF β-HUMAN CHORIONIC GONADOTROPIN (β-HCG) ON NEUTROPHIL FUNCTIONS
Immunology
Immunology
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
Many findings point to the presence of a close relationship between the
immune, endocrine and neurologic systems. For example the suppressive
effects of β-human chorionic gonadotropin (β-HCG) on IL-l production, the
potentiative effect of enkephalins on lymphocyte functions and the suppressive
effect of leuteinizing hormone (LH) on natural killer (NK) cell activities have
been clearly established. In this regard we have studied the effects of β-HCG on
neutrophil function in vitro. This study was performed on 28 peripheral blood
neutrophil samples (14 as test and 14 as control), by incubating neutrophil
preparations with bacteria in the presence or absence of the hormone for one
hour at 37°C. The results indicated that with 20 IU/mL of hormone, the total and
intracellular bactericidal activities of neutrophils were• significantly increased
(p<0.05), but the phagocytic activity remained unchanged.
Gonadotropin, human chorionic; n-eutrophil function
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-497&slc_lang=en&sid=1
M
VODJGANI
20031947532846004919
20031947532846004919
Yes
From the Dept. of Immunology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, I.R. Iran.
F
AZADI
20031947532846004920
20031947532846004920
No
J
HAJATI
20031947532846004921
20031947532846004921
No
M
KARIMIAN
20031947532846004922
20031947532846004922
No