en Surgery Surgery case report case report During the period of 1984-1995, nine young patients were admitted to Shiraz University Hospitals with a chief complaint of abdominal mass, weight loss and chronic diarrhea. Clinically, these cases were diagnosed as intestinal tuberculosis or lymphoma. Laparotomy revealed a huge mass involving the upper small intestine. Histologic sections showed diffuse infiltration of the intestinal wall with numerous mature and immature plasma cells. Serological tests showed increased levels of IgA. These cases were diagnosed and treated as immunoproliferative small intestinal disease (IPSID). Follow-up of these patients revealed that seven patients died 6-8 months after the operation and the other two patients were lost to follow-up. IPSID, Disease, Alpha heavy chain 263 266 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-364&slc_lang=en&sid=1 ABDOL RASOOL TALEI 20031947532846005117 20031947532846005117 Yes From the Departments of Surgery and Pathology, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran SEYED ALI MALEKHOSSEINI 20031947532846005118 20031947532846005118 No SEYED YAHYA ATTARAN 20031947532846005119 20031947532846005119 No SEYED MOHAMMAD OWJI 20031947532846005120 20031947532846005120 No PERIKALA V. KUMAR 20031947532846005121 20031947532846005121 No