Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1367
8
1
gregorian
1988
11
1
2
3
online
1
fulltext
en
INHIBITION OF14C UPTAKE BY CANDIDA ALBICANS: A NEW METHOD FOR INVESTIGATION OF INTRACELLULAR KILLING BY PHAGOCYTES
Biological Sciences
Biological Sciences
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
A radio assay employing 14C-uridine to measure the intracellular killing
of Candida albicans by phagocytes is presented.
The principle of this new method is that after killing of Candida albicans
by phagocytes RNA synthesis stops and therefore uridine uptake is diminished
whilst viable candida in cultures would take up uridine and as a result,
high CPM counts can be obtained within 135 min. of incubation in test
cultures. Leukocytes from 30 normal subjects showed reduced C.P.M.
following killing of Candida albicans.
237
242
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-499&slc_lang=en&sid=1
A
A. GHAVAMI NEJAD
20031947532846005602
20031947532846005602
Yes
From the Department of Biology, Faculty of Sciences, Isfahan University of Medical Sciences, Isfahan,
T
ZANDIEH
20031947532846005603
20031947532846005603
No
the Iranian Blood Transfusion Service, Tehran, Islamic Republic of Iran.