Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1367
2
1
gregorian
1988
5
1
2
1
online
1
fulltext
en
DOXYCYCLINE-INDUCED ESOPHAGEAL ULCER
Internal Medicine
Internal Medicine
Original Research
Original Research
During a period of 4 years (1983-1986), we have seen 18 patients with
esophageal ulcer following the intake of doxycycline capsules at the University
Hospitals of Shiraz Medical School. During the same period only one
other patient with a drug-induced esophageal ulcer was seen and this was
found to be due to a mefenemic acid capsule.
Diagnosis was made by esophagoscopy and after two weeks, follow-up
endoscopies revealed complete healing of the ulcers. After one year, the
follow-up observations of ten patients revealed no stricture or obstruction.
We conclude that doxycycline capsule is the single most common cause of
drug-induced esophageal ulcers and although a self-limited complication, in
already ill patients, it produces significant morbidity which could be
prevented by simple measures.
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35
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-525&slc_lang=en&sid=1
R
MALEKZADEH
20031947532846005673
20031947532846005673
Yes
From the Department of Medicine, Shiraz University of Medical Sciences, Shiraz, I.R. Iran