en Pharmacology Pharmacology Original Research: Basic Science in Medicine Original Research: Basic Science in Medicine Aluminium determination was carried out in serum and dialysis fluid by a simple and reliable method of nameless atomic absorption with graphite furnace . . No preparatory procedures are required for water and dialysis fluid. In this method serum was mixed with 0.2% HNO, to allow complete combustion of the samples in order to improve analytical precision. The method has a sensitivity of 15 pg and detection limit of 2.1 µg AI/L. The aluminium contents of the main water supply, be-distilled water and dialysis fluid were 52, I, and 44 µg/L respectively. The mean value for normal serum aluminium in Isfahan was 3.6 µg/L. Serum aluminium concentration in chronic renal failure was measured in pre- and post-dialysis samples. The mean values for the serum aluminium levels pre- and post-dialysis were 30.5 and 71.08 µg/L with a range of 9-60 and 21-123 µg/L, respectively. Pre- and post-dialysis serum aluminium values in female patients were within the range of 1-42 and 12- 66 µg/L with mean values of 18.25 and 40.5 µg/L, respectively. Instrumental settings and sample handling are discussed. 233 237 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-528&slc_lang=en&sid=1 AA MOSHTAGHIE 20031947532846005880 20031947532846005880 Yes From the Department of Biochemistry, School of Pharmacy Isfahan University of Medical Sciences, Isfahan M SANDUGHCHIN 20031947532846005881 20031947532846005881 No From the Department of Biochemistry, School of Pharmacy Isfahan University of Medical Sciences, Isfahan A BADIL 20031947532846005882 20031947532846005882 No From the Department of Biochemistry, School of Pharmacy Isfahan University of Medical Sciences, Isfahan M AZANI 20031947532846005883 20031947532846005883 No the Dialysis Center, Shariati Hospital, Isfahan, I.R. Iran.