en Internal Medicine Internal Medicine Original Research Original Research Visceral leishmaniasis is the second most common cause of fever of unknown origin in our study. This disease is not common in adults, although it's endemic among the pediatric age group. The majority of the affected individuals were young. High grade spiking fever, chills and splenomegaly were unique findings. Other common findings were neutropenia, anemia, abnormal liver function tests, sterile pyuria and microscopic hematuria. Except for I case, parasites were absent from tissue biopsies (e.g. bone marrow, liver, lymph node). Diagnosis was suggested by indirect fluorescent antibody (IFA) and confirmed by response to meglumine antimonate (Glucantime) and decline of IFA titer on follow-up. F.U.O .. Leishmaniasis. 97 100 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-589&slc_lang=en&sid=1 GHR OMRANI 20031947532846006056 20031947532846006056 Yes From the Departments of Internal Medicine Medical School, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. A FARHADl 20031947532846006057 20031947532846006057 No From the Departments of Internal Medicine Medical School, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. A PARHlZGAR 20031947532846006058 20031947532846006058 No From the Departments of Internal Medicine Medical School, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. S ARDEHALl 20031947532846006059 20031947532846006059 No From the Departments of Microbiology, Medical School, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran. M HAGHSHENAS 20031947532846006060 20031947532846006060 No From the Departments of Internal Medicine Medical School, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.