Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1373
2
1
gregorian
1994
5
1
8
1
online
1
fulltext
en
DEVELOPMENT OF A RAPID AND SENSITIVE RADIOIMMUNOASSAY FOR MEASUREMENT OF AFLATOXIN B 1 IN BIOLOGICAL SAMPLES
Biological Sciences
Biological Sciences
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
Aflatoxin B I (AFB) isa well known hepatocarcinogen in several animal species
and probably a causative agent in human hepatocellular carcinoma. Humans are
exposed to AFB by ingesting contaminated food. Aflatoxin contamination encountered
in human foods is usually at low levels which is difficult to measure by chromatographic
methods. Therefore in the present study we have developed an immunoassay for APB
detection which is specific, sensitive and reliable. This method is applicable to a variety
of biological samples such as food products, serum, milk, urine, etc. The antibody
produced against AFB-bovine serum a1bwnin is highly specific with a low cross
reactivity towards structurally-related aflatoxins. Other characteristics of this method
including assay validation, reproducibility. recovery and statistical validations are
discussed. We suggest the use of this technique as a routine method for screening food
products designated for human consumption.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-605&slc_lang=en&sid=1
A
TOTONCHI
20031947532846006097
20031947532846006097
Yes
From the Department of Biochemistry, School of Medical Sciences, Tarbiat Modarres University, Tehran, Islamic Republic of Iran.
MJ
RASAEE
20031947532846006098
20031947532846006098
No
AA
ALLAMEH
20031947532846006099
20031947532846006099
No
GR
ASSADIKARAM
20031947532846006100
20031947532846006100
No
SA
MESBAH
20031947532846006101
20031947532846006101
No