Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1372
8
1
gregorian
1993
11
1
7
3
online
1
fulltext
en
A STUDY OF 765 CASES OF CLINICALLY SOLITARY COLD THYROID NODULES FROM AN IODINEDEFICIENT AREA
Internal Medicine
Internal Medicine
Original Research
Original Research
We studied the clinical, radioisotopic, and pathologic characteristics and the
incidence of cancer in clinically solitary cold nodules of the thyroid in an iodinedeficient
area. The study included retrospective analysis of 765 patients who
underwent thyroidectomy for a clinically single cold nodule in a ten-year period. We
compared the pathological findings with clinical data. In pathological examination,
34% of glands were multinodular. The incidence of nodular colloid goiters were
81.7% and of thyroid cancer 10.2%. Thyroid malignancy increased significantly
after age thirty (p<0.005). The incidence of cancer was 8.3% in true solitary nodules
versus 13.8% in clinically solitary nodules found to be pathologically multinodular
(p<0.05). Papillary carcinoma was the most frequent type (70.5%) and medullary
carcinoma the least frequent type (2.6%). Benign nodular lesions were the most
common cause of cold nodules. There was no sex difference in the incidence of
thyroid cancer. In the patients with thyroid carcinoma the percentage of multinodular
glands was higher. Iodine deficiency may be a factor in changing certain characteristics
of thyroid nodules.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-623&slc_lang=en&sid=1
MANOOCHEHR
NAKHJAVANI
20031947532846006137
20031947532846006137
Yes
From the Department of Internal Medicine, Division of Endocrinology and Metabolism, Tehran University of Medical Sciences,
MOHAMMAD HASAN
BASTANHAGH
20031947532846006138
20031947532846006138
No
REZA
KASSAYAN
20031947532846006139
20031947532846006139
No
RADINA
ESHTIAGHI
20031947532846006140
20031947532846006140
No
AFSAR
ASADI
20031947532846006141
20031947532846006141
No
MOHAMMAD
RAJAI
20031947532846006142
20031947532846006142
No