en Pharmacology Pharmacology Original Research: Basic Science in Medicine Original Research: Basic Science in Medicine The new phase-II N-glucoside metabolites of butobarbitone and pentobarbitone are identified and quantified in human urine after single doses of these drugs. The identification and quantification of these metabolites were carried out by mass spectroscopy technique (accurate mass measurement and high voltage scanning). It was found that the butobarbitone N-glucoside comprised 26% of the dose with tl/2= 44h, while the pentobarbitone N-glucoside was 43% with t1/2= 40h. 63 66 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-713&slc_lang=en&sid=1 MA AL-SHARIFI 20031947532846006358 20031947532846006358 Yes From the Department of Pharmacology, Qazvin University of Medical Sciences, Qazvin, Islamic Republic of Iran.