Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1370
6
1
gregorian
1991
9
1
5
1
online
1
fulltext
en
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC ANALYSIS OF SULFUR MUSTARD REACTION WITH AMINO ACIDS AND PROTEINS
Biological Sciences
Biological Sciences
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
The interaction of sulfur mustard with aminoacids and proteins has
been investigated in this study. Rats were injected with sublethal doses of
sulfur mustard subcutaneously and intraperitoneally. At different time
intervals, plasma and urine samples were collected. The binding affinity of
sulfur mustard with urinary and plasma proteins and enzymes was studied for
the first time using non-ideal size exclusion high-performance liquid chromatography
(HPLC). We observed that sulfur mustard reacts with proteins and
enzymes containing cystein, arginine, and lysine residues.
55
58
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-726&slc_lang=en&sid=1
D
QUJEQ
20031947532846006397
20031947532846006397
Yes
From the Dept. of Biochemistry, Tarbiat Modarres University, Tehran, Islamic Republic of Iran.
M
TAGHIKHANI
20031947532846006398
20031947532846006398
No