Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1369
8
1
gregorian
1990
11
1
4
4
online
1
fulltext
en
EVALUATION OF CELL-MEDIATED IMMUNITY IN MUSTARD GAS INJURIES
Legal Medicine
Original Research
Original Research
Yamakido, et al. in 1986 have studied immunological parameters in
poison gas workers, and a depression has been observed in immunologic
response. Also, the frequency of cancer has reached as high as five-fold that
of the general population. In the present study, cell-mediated immunity
(CMI) was measured in three groups of Iranian mustard gas-injured
patients.
The first group were those who had been injured three months up to one
year before, and the second group were studied one to two years after in jury,
and the third. group were studied after two years from the time of injury. The
following results were obtained:
1- In comparison with normal controls (61.5±4), T lymphocytes
showed a significant decrease in 50% of the three groups (50.71±15. 7
46.95±15) of poison gas injury, and B lymphocytes were increased, but no
significant difference could be seen in mitogen response to PHA.
2- In comparison with normal control (47 ±9), T helpercells (T4) in 52%
of the first and second groups were significantly decreased (33. 14± 16.59).
3- T suppressor cells (T8) in 53% of the first group, and in 22% of the
second and third groups (27.29±11. 77 21. 4±6. 89) were increased in
comparison with normal controls (20±6).
4- Ratio of T4 to T8 in 71 010" of the first group and 60% of the second and
third groups were decreased. Therefore depression of CMI in poison gas
injury was observed after one, two, and three years, which will be discussed
in this paper.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-732&slc_lang=en&sid=1
T
ZANDIEH
20031947532846006408
20031947532846006408
Yes
From the Iranian Blood Transfusion Center, Villa Ave, No.J38, Tehran, Islamic Republic of Iran.
S
MARZBAN
20031947532846006409
20031947532846006409
No
G
HASSIRI
20031947532846006410
20031947532846006410
No
F
TARABADI
20031947532846006411
20031947532846006411
No
H
ANSARI
20031947532846006412
20031947532846006412
No