en Surgery Surgery Original Research: Basic Science in Medicine Original Research: Basic Science in Medicine Twenty-two recipients of HLA-nonidentical living related and nonrelated renal allografts were studied for alterations in the relative percentage of OKT4-positive peripheral blood T-cells after transplantation. Characteristic shifts in the ratio of T-helper to T -suppressor/cytotoxic cells (TH/TS-C), but not absolute cell numbers, were demonstrated to correspond with the status of the allograft. Our results are indicative of a correlation between rejection episodes and the increase in OKT4:0KT8 ratios, that were characterized by a significant rise in the percentage of OKT4-positive cells (P=0.001), and a decrease in the percentage of OKT8-positive cells (P=0.001). 47 52 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-771&slc_lang=en&sid=1 M NOBAKHT 20031947532846006518 20031947532846006518 Yes From the' Department of Histology, Tarbiat Modarres University N SIMFOROOSH 20031947532846006519 20031947532846006519 No Department of Kidney Transplantation, ALI MOHAMADIAN 20031947532846006520 20031947532846006520 No the Pasteur Institute, Tehran, Islamic Republic of lran B AMIR-ANSARI 20031947532846006521 20031947532846006521 No