Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1370
8
1
gregorian
1991
11
1
5
3
online
1
fulltext
en
THE STUDY OF OPSONIZATION ACTIVITY OF THE PHAGOCYTOSIS PROCESS IN MENINGITIS, SEPSIS, AND RECURRENT INFECTION IN CHILDREN
Immunology
Immunology
Original Research
Original Research
In this survey, opsonization activity of sera in 110 patients with
meningitis, sepsis and recurrent infection 12 patients after healing and 50
normal adults has been studied. Opsonization activity was measured by an
assay depending on electronic particle counting to measure yeast uptake
(alternative pathway activator) which was modified in our laboratory.
Three classes of immunoglobulins (lgG, lgM, lgA) and C3 levels were
also studied depending on single radial immunodiffusion by using Behring
kit in our patients.
54 pathological sera with defective opsonization showed low C3 levels,
two with lower than normal opsonization activity showed low C3 levels, 11
defective opsonization cases showed normal C3 levels, 3 of which were
related to diabetic patients.
22 instances of decreased 19G, 14 cases of decreased 19M and 18 cases of
decreased lgA were observed in 110 patients.
The opsonization activity, C3 and immunoglobulin levels in 12 patients
have become normal after healing.
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129
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-818&slc_lang=en&sid=1
S
NEZAM DIBA
20031947532846006740
20031947532846006740
Yes
From the Department of Immunology, the Children's Hospital Medical Center, Tehran university of Medical Sciences, Tehran, Islamic Republic of Iran.
A
FARHOUDI
20031947532846006741
20031947532846006741
No