Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1370
8
1
gregorian
1991
11
1
5
3
online
1
fulltext
en
TREATMENT OF PRECOCIOUS PUBERTY BY A LONG-ACTING GONADOTROPIN-RELEASING HORMONE ANALOGUE IN CHILDREN
Pediatric
Pediatric
Original Research: Basic Science in Medicine
Original Research: Basic Science in Medicine
The GnRH analogue has been shown to be effective in the treatment of
precocious puberty when given as a daily subcutaneous injection. We studied
the effectiveness of a long-acting GnRH analogue, Triptoreline, for the
treatment of central precocity, by suppressing gonadotropin and estradiol
secretion in three children with true precocious puberty. One month after
single dose intramuscular injection of depot GnRH analog Triptoreline, our
patients showed significant decreases in serum estradiol and blunting of the
responses of LH and FSH to GnRH test. No adverse effects were noted
during the first six to eight months of treatment.
159
161
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-827&slc_lang=en&sid=1
F
MOSTAFAVI
20031947532846006766
20031947532846006766
Yes
rom the Department of Pediatric Endocrinology, Children's Hospital Medical Center of Ahari, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
A
RABBANI
20031947532846006767
20031947532846006767
No