Medical Journal of the Islamic Republic Of Iran

en Evaluation of liver and kidney function in favism patients Hematology Hematology Original Research Original Research Backgrounds: G6PD deficiency is the most common enzymopathy of red blood cells. The clinical symptoms of favism are jaundice, hematuria and haemolytic anaemia that seem to affect liver and kidney in long term. Thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a high rate of fava beans cultivation. Methods: This study was performed on favism patients and healthy controls referring to Iranshahr central hospital. Liver and kidney function tests were performed. Results: The results showed a statistically significant difference between these two groups (p <0.05) for liver function tests, (AST, ALT and ALP), but not for renal tests (BUN and creatinine) (p >0.05). Conclusion: Due to abnormalities were seen in the liver function tests of these patients, we suggest that these tests be regularly performed for favism patients who are constantly exposed to oxidant agents. G6PD, Favism, Liver, Kidney. 17 22 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-562&slc_lang=en&sid=1 Akbar Dorgalaleh dorgalaleh.1390@yahoo.com 20031947532846007369 20031947532846007369 No Hematology Department, Allied Medical School, Tehran University of Medical Sciences, Tehran, Iran. Muhammad Shahid Shahzad onlyshahid@yahoo.com 20031947532846007370 20031947532846007370 No Iran Hospital, Nikshahr, Iran. Mohammad Reza Younesi mohammadrezayounesi@yahoo.com 20031947532846007371 20031947532846007371 No Hematology Department, Allied Medical School, Tehran University of Medical Sciences, Tehran, Iran. Esmaeil Sanei Moghaddam saso1334@yahoo.com 20031947532846007372 20031947532846007372 No High Institute for Research and Education in Transfusion Medicine and ZahedanRegional Educational Blood Transfusion Center, Iran. Mohammad Mahmoodi newassistant@yahoo.com 20031947532846007373 20031947532846007373 No Golestan, Minoodasht, Iran. Bijan Varmaghani bijan_varmaghani@yahoo.com 20031947532846007374 20031947532846007374 No Hematology Department, Allied Medical School, Tehran University of Medical Sciences, Tehran, Iran. Zahra Kashani Khatib zkashanikhatib@gmail.com 20031947532846007375 20031947532846007375 No Student of Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran. Shaban Alizadeh alizadehs@sina.tums.ac.ir 20031947532846007376 20031947532846007376 Yes Hematology Department, Allied Medical School, Tehran University of Medical Sciences, Tehran, Iran.