en Pediatric Nephrology Pediatric Nephrology Original Research Original Research <p> <strong>Abstract</strong></p><p> <strong>Background:</strong> Clinical Risk Index of Babies (CRIB), Score for Neonatal Acute Physiology</p><p> (SNAP), an update of the Clinical Risk Index for Babies score (CRIB II) and</p><p> Score for Neonatal Acute Physiology - Perinatal Extension (SNAP-PE) are scoring devices</p><p> developed in neonatal intensive care units. This study reviewed these scoring systems</p><p> in critically ill neonates to determine how well they could predict mortality.</p><p> <strong>Methods: </strong>This prospective cohort study was conducted at the neonatal intensive care</p><p> units of Mofid and Mahdieh hospitals between March 2006 and May 2009. We evaluated</p><p> CRIB, CRIB II, SNAP, SNAPII and SNAP-PE score for each neonate and the final</p><p> scores were then obtained. The predictive accuracy of these parameters were expressed</p><p> as area under the receiver operative characteristic curve, sensitivity, specificity, positive</p><p> predictive value and negative predictive value.</p><p> <strong>Results:</strong> Of 404 neonate evaluated 53% were male. Primary diagnoses were respiratory</p><p> distress syndrome, gastrointestinal obstruction, sepsis, prematurity, and neuromuscular</p><p> diseases. The authors detected mortality in 20.5% and found a significant difference</p><p> in scoring systems between survived and death groups. The mean CRIB score in</p><p> survived neonates was 2.57±3.66 and in death neonates 8.43±4.66 (p value<0.001). We</p><p> also found that the SNAP score had the highest area under the curve and the highest sensitivity,</p><p> specificity, positive predictive value, negative predictive value and we had the</p><p> lowest score for CRIB II.</p><p> <strong>Conclusion:</strong> We concluded that the neonatal scoring systems could be a useful tool</p><p> for prediction of mortality in NICUs and SNAP can predict the mortality better than the</p><p> others.</p> CRIB, CRIB II, SNAP, SNAPII, SNAP-PE, mortality, neonates, outcome, scoring system 193 199 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-126&slc_lang=en&sid=1 Masoumeh Mohkam Mohkamm@pirc.ir 20031947532846001328 20031947532846001328 Yes Mofid Children's Hospital Shariati Ave. Tehran, Iran. Shahid Beheshti Abolfazl Afjeii A_afjehi@sbmu.ac.ir 20031947532846001329 20031947532846001329 No Mofid Children's Hospital, SBMU Paiam Payandeh 20031947532846001330 20031947532846001330 No Masoud Zadkarami 20031947532846001331 20031947532846001331 No Mohammad Kazemian 20031947532846001332 20031947532846001332 No Hossein Fakhraii 20031947532846001333 20031947532846001333 No Shahin Nariman 20031947532846001334 20031947532846001334 No Fatemeh Abdollah Gorgi 20031947532846001335 20031947532846001335 No