Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1392
10
1
gregorian
2014
1
1
28
1
online
1
fulltext
en
Rare Association of Severe Cryptococcal and Tuberculosis in Central Nervous System in a case of Sarcoidosis
Infectious Disease
Infectious Disease
case report
case report
<p> Sarcoidosis is a multisystem noncaseating granulomatous disease with a propensity for lung, eye, and skin which recently have been proposed that mycobacterium tuberculosis may contribute in its pathogenesis, and rarely involves central nervous system (CNS). Despite CD4+ lymphocytopenia, sarcoidosis by itself does not increase risk of opportunistic infections other than cryptococcosis.Nonetheless, simultaneous association of CNS cryptococcosis and tuberculosis infection remains extremely rare event in immunocompetent states, and has not been reported in sarcoidosis yet. We here presented such a case ina 42 years old man, a known case of sarcoidosis with diagnostic and therapeutic difficulties were encountered in a fourteen-month-long hospitalization period. </p>
Sarcoidosis, ventriculomeningitis, hydrocephalus, cryptococcosis, Tuberculosis.
138
143
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-650&slc_lang=en&sid=1
Bahaadin
Siroos
bsiroos@gmail.com
200319475328460012945
200319475328460012945
No
Imam Khomeini Hospital, Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
Zahra
Ahmadinejad
ahmadiz@tums.ac.ir
200319475328460012946
200319475328460012946
No
Imam Khomeini Hospital, Department of Infectious Disease, Tehran University of Medical Sciences, Tehran, Iran.
Mohamad
Tabaeizadeh
motif42@gmail.com
200319475328460012947
200319475328460012947
No
Imam Khomeini Hospital, Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
Mojtaba
Hedayat Yaghoobi
newdrmy@yahoo.com
200319475328460012948
200319475328460012948
No
Imam Khomeini Hospital, Department of Infectious Disease, Tehran University of Medical Sciences, Tehran, Iran.
Alireza
Torabi
abghsa@gmail.com
200319475328460012949
200319475328460012949
No
Imam Khomeini Hospital, Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.
Majid
Ghaffarpour
ghafarpour@sina.tums.ir
200319475328460012950
200319475328460012950
Yes
Iranian Center of Neurological Research, Tehran University of Medical Sciences, Tehran, Iran.