en Gastroenterology Gastroenterology Original Research Original Research <p> <strong> Background: </strong>Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago. </p><p> <strong> Methods </strong>: One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria. </p><p> <strong> Results </strong>: 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155). </p><p> <strong> Conclusion </strong>: Based on our findings, SM exposure seems not to be associated with increased esophagitis. </p><p> <strong> </strong></p> Sulfur mustard, Esophagitis, Gastroesophageal reflux. 188 191 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-659&slc_lang=en&sid=1 Nader Roushan nroshan@tums.ac.ir 200319475328460012900 200319475328460012900 Yes Department of Internal Medicine, Division of Gastroenterology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Fateme Zali zali.fateme@gmail.com 200319475328460012901 200319475328460012901 No Imam Khomeini Hospital, Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences. Hamidreza Abtahi hrabtahi@tums.ac.ir 200319475328460012902 200319475328460012902 No Advanced Thoracic Research Center, Pulmonary and Critical Care Department, Imam Khomeini Hospital, Tehran University of Medical Sciences. Mehrnaz Asadi mehrnazasadi@yahoo.com 200319475328460012903 200319475328460012903 No Department of Internal Medicine, Imam Khomeini Hospital ,Tehran University of Medical Sciences, Tehran, Iran. Reza Taslimi rtaslimi@tums.ac.ir 200319475328460012904 200319475328460012904 No Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran. Najme Aletaha aletaha@ddrc.ac.ir 200319475328460012905 200319475328460012905 No Department of Internal Medicine, Division of Gastroenterology, Tehran University of Medical Sciences, Tehran, Iran.