en Nursing Education Nursing Education Original Research Original Research <p> <strong> Background: </strong>Epidemiological changes leading to chronic diseases are becoming more important day by day. Hypertension is also known as a chronic disease. Worldwide prevalence of hypertension have caused serious complications. The disease has become a health problem in all communities. This research aims at analyze the correlation between compliance with the treatment regimen and health locus of control in hypertension patients. </p><p> <strong> Methods </strong>: In this study, 130 patients diagnosed with high blood pressure have been included using convenience sampling. Information has been gathered including demographic data, compliance with the treatment regimen and health locus of control. The patient's blood pressure was measured twice and the mean was compared with the first blood pressure recorded in medical records. Data were analyzed using SPSS 17. </p><p> <strong> Results </strong>: The results showed that there is a direct correlation between the adherence to the treatment regimen with internal health locus of control. In patients with internal health locus of control, better compliance with treatment regimen was detected. </p><p> <strong> Conclusion </strong>: Health locus of control is associated with treatment regimen. Considering health locus control can help nurses and managers in their health programs and also can motivate patients to participate in their self-care and improve patients care quality. </p><p> <strong> </strong></p> hypertension, treatment, health, locus. 288 291 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-808&slc_lang=en&sid=1 Mohammad Taher Tahermohammad38@gmail.com 200319475328460015414 200319475328460015414 No Nursing Department, Faculty of Nursing and Midwifery, Saveh University of Medical Sciences, Saveh, Iran. Zahra Safavi Bayat Zahrasb16@yahoo.com 200319475328460015415 200319475328460015415 Yes Medical-Surgical Department, Faculty of Nursing and Midwifery, ShahidBeheshti University of Medical Sciences, Tehran, Iran. Kianoush Niromand zandi n.zandi@yahoo.com 200319475328460015416 200319475328460015416 No Medical-Surgical Department, Faculty of Nursing and Midwifery, ShahidBeheshti University of Medical Sciences, Tehran, Iran. Erfan Ghasemi ghasemi.erfan87@yahoo.com 200319475328460015417 200319475328460015417 No Shahid Beheshti University of Medical Sciences, Tehran, Iran. Hamid Abredari hamid_abredari@yahoo.com 200319475328460015418 200319475328460015418 No Nursing Department, Faculty of Nursing and Midwifery, Saveh University of Medical Sciences, Saveh, Iran. Mahmood Karimy 200319475328460015419 200319475328460015419 No Health Education and Health Promotion Department, Saveh University of Medical Sciences, Saveh, Iran. Ahmad Reza Abedi abedi30@yahoo.co.uk 200319475328460015420 200319475328460015420 No Medical-Surgical Department, Faculty of Nursing & Midwifery, Arak university of Medical Sciences , Arak , Iran.