Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1393
10
1
gregorian
2015
1
1
29
1
online
1
fulltext
en
Therapeutic effects of Ventolin versus hypertonic saline 3% for acute bronchiolitis in children
Pediatric
Pediatric
Original Research
Original Research
<p> <strong> Background: </strong>Complications of Ventolin as the most common drug used for bronchiolitis are widely known. The present study was conducted to determine the efficacy of hypertonic saline 3%, compared with Ventolin, for treatment of acute bronchiolitis in children. </p><p> <strong> Methods </strong>: This double-blinded clinical trial study was conducted in Hajar Hospital, Shahrekord, Iran, from 2011 to 2012. A total of 70 patients under the age of two years with bronchiolitis were divided into two groups of 35 each. Ventolin nebulizer and hypertonic saline 3% nebulizer three times per day were administered in the first (Ventolin) and second (Hypersaline) group, respectively. The length of recovery was compared between the two groups. The data were analyzed by SPSS software (version 22) using chi-square, t-test, paired t-test, and Mann-Whitney. </p><p> <strong> Results </strong>: The mean±SD length of recovery was 4.14±0.9 and 3.06±0.6 in the Ventolin and hypersaline groups, respectively. The mean duration of recovery was significantly lower in the hypersaline group (p<0.001). </p><p> <strong> Conclusion </strong>: Hypertonic saline 3% nebulizer has more pleasant therapeutic effects on acute bronchiolitis than Ventolin. Therefore, use of hypertonic saline 3% nebulizer is recommended for the treatment of acute bronchiolitis in children under two years old. </p>
Hypertonic saline solution, Pediatric, Bronchiolitis, Ventolin-albuterol.
428
432
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-831&slc_lang=en&sid=1
Mohammad-Ali
Zamani
zamani@yahoo.com
200319475328460016429
200319475328460016429
No
Department of Pediatrics, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mehran
Movahhedi
alirezannfor@yahoo.com
200319475328460016430
200319475328460016430
No
Department of Pediatrics, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Seyyed Mohammad-Kazem
Nourbakhsh
dr.nourbakhsh2010@gmail.com
200319475328460016431
200319475328460016431
No
Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.
Forouzan
Ganji
foruzan2000@yahoo.co.in
200319475328460016432
200319475328460016432
No
Department of Community Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mahmoud
Rafieian-Kopaei
rafieian@yahoo.com
200319475328460016433
200319475328460016433
No
Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Mahmoud
Mobasheri
mobasheri@skums.ac.ir
200319475328460016434
200319475328460016434
No
Department of Epidemiology, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Abolfazl
Khoshdel
nikakhosh@gmail.com
200319475328460016435
200319475328460016435
No
Department of Pediatrics, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Shahram
Etemadifar
shahram_410@yahoo.com
200319475328460016436
200319475328460016436
No
Department of Nursing, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Majid
Shirani
shirani.m@skums.ac.ir
200319475328460016437
200319475328460016437
No
Department of Surgery, Shahrekord University of Medical Sciences, Shahrekord, Iran
Zahra
Keivani Hafshejani
keivaniz@yahoo.com
200319475328460016438
200319475328460016438
Yes
Shahrekord University of Medical Sciences, Shahrekord, Iran.