en Gynecology & Obstetrics Gynecology & Obstetrics Review Article Review Article <p><strong>Background:</strong> Caesarean section (C-section) is the most common surgery among women worldwide, and the global rate of this surgical<br> procedure has been continuously rising. Hence, it is significantly crucial to develop and apply highly effective and safe caesarean<br> section techniques. In this review study, we aimed at assessing the safety and effectiveness of the Joel-Cohen-based technique and<br> comparing the results with the transverse Pfannenstiel incision for C-section.<br> <strong>Methods:</strong> In this study, various reliable databases such as the PubMed Central, COCHRANE, DARE, and Ovid MEDLINE were<br> targeted. Reviews, systematic reviews, and randomized clinical trial studies comparing the Joel-Cohen-based technique and the transverse<br> Pfannenstiel incision were selected based on the inclusion criteria. Selected studies were checked by 2 independent reviewers<br> based on the inclusion criteria, and the quality of these studies was assessed. Then, their data were extracted and analyzed.<br> <strong>Results:</strong> Five randomized clinical trial studies met the inclusion criteria. According to the exiting evidence, statistical results of the<br> Joel-Cohen-based technique showed that this technique is more effective compared to the transverse Pfannenstiel incision. Metaanalysis<br> results of the 3 outcomes were as follow: operation time (5 trials, 764 women; WMD -9.78; 95% CI:-14.49-5.07 minutes,<br> p<0.001), blood loss (3 trials, 309 women; WMD -53.23ml; 95% &ndash;CI: 90.20-16.26 ml, p= 0.004), and post-operative hospital stay (3<br> trials, 453 women; WMD -.69 day; 95% CI: 1.4-0.03 day, p<0.001). Statistical results revealed a significant difference between the 2<br> techniques.<br> <strong>Conclusion: </strong>According to the literature, despite having a number of side effects, the Joel-Cohen-based technique is generally more<br> effective than the Pfannenstiel incision technique. In addition, it was recommended that the Joel-Cohen-based technique be used as a<br> replacement for the Pfannenstiel incision technique according to the surgeons&rsquo; preferences and the patients&rsquo; conditions.</p> Caesarean Section (C-section), Joel-Cohen, Pfannenstiel, Misgav-Ladach, Modified Misgav-Ladach 313 318 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-2280-1&slc_lang=en&sid=1 Alireza Olyaeemanesh arolyaee@gmail.com 200319475328460033980 200319475328460033980 No National Institute for Health Research, Tehran University of Medical Sciences, Tehran, Iran. Elahe Bavandpour el.bavandpour@gmail.com 200319475328460033981 200319475328460033981 Yes Tehran University of Medical Sciences, Tehran, Iran. Mohammadreza Mobinizadeh mobinreza@yahoo.com 200319475328460033982 200319475328460033982 No National Institute for Health Research, Tehran University of Medical Sciences, Tehran, Iran. Mansoor Ashrafinia mansor@gmail.com 200319475328460033983 200319475328460033983 No Arash University Hospital, Tehran University of Medical Sciences, Tehran, Iran. Maryam Bavandpour m.bavandpour 1108@gmail.com 200319475328460033984 200319475328460033984 No Tehran University of Medical Sciences, Tehran, Iran. Mojtaba Nouhi mojtabanouhi@gmail.com 200319475328460033985 200319475328460033985 No School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.