Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1386
8
1
gregorian
2007
11
1
21
3
online
1
fulltext
en
Can mustard gas induce late onset polyneuropathy?
Midwifery and Reproductive Health
Original Research
Original Research
<p> <strong>Abstract</strong></p><p> <strong>Background:</strong> Mustard gas, lethal in high doses, affects multiple organs such as skin, eye and respiratory system. We studied the development of late onset mustardinduced polyneuropathy among chemically wounded Iranian veterans.</p><p> <strong>Methods:</strong> In this descriptive study, 100 chemically wounded Iranian veterans with severe eye involvement were examined for any signs and symptoms of polyneuropathy by an internist. 20 patients were suspected to have neurological symptoms or signs. These patients were examined by a neurologist again. 13 showed abnormal neurological symptoms. Electrodiagnostic exams were performed for this group by another physician.</p><p> <strong>Results:</strong> 13 veterans had abnormal neurological exam results with prominent sensory signs and symptoms in almost all of them. Brisk deep tendon reflexes were found in 3 cases. Electrodiagnostic studies were compatible with axonal type distal sensory polyneuropathy in 6 subjects.</p><p> <strong>Conclusion:</strong> To the best of our knowledge, this is the first report of late onset polyneuropathy among chemically-wounded victims who were exposed to mustard gas. The pathophysiology of this form of neuropathy is still unknown. Unlike most toxic neuropathies, obvious clinical signs and symptoms appeared several years after exposure. No specific treatment for polyneuropathy due to chemical weapons exposure has been described to date.</p>
mustard gas, polyneuropathy, chemical weapon
145
150
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-178&slc_lang=en&sid=1
MR.
Azarpazhooh
r_azarpazhooh@yahoo.com
20031947532846002177
20031947532846002177
Yes
Mashhad University of Medical Sciences, No.380, Sajad blvd, Mashhad, Iran
A.
Shoeibi
20031947532846002178
20031947532846002178
No
Mashhad University of Medical Sciences
MR.
Soroush
20031947532846002179
20031947532846002179
No
Janbazan Medical Engineering Research Center, Mashhad, Iran
S.
Khateri
20031947532846002180
20031947532846002180
No
Janbazan Medical Engineering Research Center, Mashhad, Iran
SJ.
Mousavi
20031947532846002181
20031947532846002181
No
Janbazan Medical Engineering Research Center, Mashhad, Iran
E.
Modirian
20031947532846002182
20031947532846002182
No
Janbazan Medical Engineering Research Center, Mashhad, Iran