Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1394
10
1
gregorian
2016
1
1
30
1
online
1
fulltext
en
Combined effect of botulinum toxin and splinting on motor components and function of people suffering a stroke
Occupational Therapy
Occupational Therapy
Original Research
Original Research
<p dir="ltr" style="text-align: justify;"><strong>Background: </strong>Spasticity is one of the problems after a stroke. Due to this increase in muscle tone, patients are confronted with problems in motor control and difficulties in activities of daily living and complications such as shortness and contracture. The aim of this study was to examine the effects of the simultaneous use of both splint and botulinum toxin-A (BTX-A) injection on spasticity, range of motion and upper extremity function in a 3-month period.</p>
<p dir="ltr" style="text-align: justify;"><strong> Methods</strong>: In this study a comparison was done between three groups of interventions, conducted in rehabilitation clinics in Tehran. Sixty people with chronic stroke were recruited. Based on the inclusion criteria, a total of 39 stroke patients after completing the consent forms were entered to intervention groups; splint or botulinum toxin injection or combined splint/botulinum toxin injection. They were followed up about three months and the evaluations were done monthly. Goniometry was the method to measure the range of motion, and Modified Ashworth Scale was used to examine the spasticity and the upper extremity function was scored based on Fugl-Meyer Assessment. Statistical analysis was done using SPSS 17. And ANOVAs was used for comparison between groups and times. Significance was set at 0.05.</p>
<p dir="ltr" style="text-align: justify;"><strong> Results</strong>: All outcome measures were improved within each group but the differences between splint group and BTX-A group and the BTX-A-splint group was not significant in most outcomes during the 3 periods (first evaluation until end of the first month, the end of first month until the end of second month, the end of second month until the end of the third month) (p>0.05). The results also showed that the changes in elbow`s spasticity (p=0.05) and wrist`s spasticity (p=0.007) and upper extremity function (p=0.04) were obvious between the three groups over the 3-months and the difference in the group of combined use of botulinum toxin, and the splint was more than other groups.</p>
<p dir="ltr" style="text-align: justify;"><strong> Conclusion</strong>: In this study, the effects of botulinum toxin injection and Volar-Dorsal Wrist/Hand Immobilization splint and the combined use of botulinum injection and splint were obvious in all groups but was not significantly different between the interventions in a 3-month follow-up.</p>
Splinting, Botulinum toxin, Stroke, Hand function.
511
517
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-1005&slc_lang=en&sid=1
Malek
Amini
200319475328460023892
200319475328460023892
No
Occupational Therapy Department, Faculty of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.
Aryan
Shamili
shamilia@tbzmed.ac.ir
200319475328460023893
200319475328460023893
Yes
Iran University of Medical Sciences, Tehran, Iran, & Lecturer at Rehabilitation Faculty and Neurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Bijan
Frough
bijanfr@gmail.com
200319475328460023894
200319475328460023894
No
Iran University of Medical Sciences, Tehran, Iran.
Marzieh
Pashmdarfard
ghazal.ot.fard@yahoo.com
200319475328460023895
200319475328460023895
No
Zanjan University of Medical Sciences, Zanjan, Iran.
Abolghasem Fallahzadeh
Abarghouei
msc.fallahzadeh@gmail.com
200319475328460023896
200319475328460023896
No
Iran University of Medical Sciences, Tehran, Iran.