en Epidemiology Epidemiology Original Research Original Research <p style="text-align: justify;"><strong>Background: </strong>More than 20% of deaths from traffic crashes are related to pedestrians. This figure in Tehran, the capital of Iran, reaches to 40%. This study aimed to determine the high-risk areas and spatially analyze the traffic crashes, causing death to pedestrians in Tehran.</p> <p style="text-align: justify;"><strong>&nbsp; Methods:</strong> Mapping was used to display the distribution of the crashes. Determining the distribution pattern of crashes and the hot spots/ low-risk areas were done, using Moran&rsquo;s I index and Getis-Ord G, respectively.</p> <p style="text-align: justify;"><strong>&nbsp; Results:</strong> A total of 198 crashes were studied; 92 of which, (46.4%) occurred in 2013 to 2014 and other 106 cases (63.6%) occurred in 2014 to 2015. The highest and the lowest frequency of crashes was related to January (26 cases) and June (10 cases), respectively. One hundred fifty- eight cases (79.8%) of crashes occurred in Tehran highways. Moran&rsquo;s index showed that the studied traffic crashes had a cluster distribution (p<0.001). Getis-Ord General G index indicated that the distribution of hot and cold spots of the studied crashes was statistically significant (p<0.001).</p> <p style="text-align: justify;"><strong>&nbsp; Conclusion:</strong> The majority of traffic crashes causing death to pedestrians occurred in highways located in the main entrances and exits of Tehran. Given the important role of environmental factors in the occurrence of traffic crashes related to pedestrians, identification of these factors requires more studies with casual inferences.</p> Spatial Analysis, Road traffic injury, Pedestrians. 1099 1108 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-1083&slc_lang=en&sid=1 Ali Moradi amoradi1350@yahoo.com 200319475328460025848 200319475328460025848 No Department of Epidemiology, Faculty of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Hamid Soori hsoori@yahoo.com 200319475328460025849 200319475328460025849 Yes Safety Promotion and Injury Prevention Research Center, School of Public Health, Shahid Beheshti University, Tehran, Iran. Amir Kavousi kavousi_am@yahoo.com 200319475328460025850 200319475328460025850 No School of Health, Safety and Environment, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Farshid Eshghabadi farshid.e2012@Outlook.com 200319475328460025851 200319475328460025851 No Faculty of Geography, Department of Human Geography/Urban Planning, University of Tehran, Tehran, Iran. Ensiyeh Jamshidi ensiyeh_jamshidi@yahoo.com 200319475328460025852 200319475328460025852 No Community Based Participatory Research Center, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran. Salahdien Zeini sszeini@yahoo.com 200319475328460025853 200319475328460025853 No Colonel of Road Traffic Police, Crashes office, Tehran's Traffic Police, Tehran, Iran.