Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1394
10
1
gregorian
2016
1
1
30
1
online
1
fulltext
en
Assessment of nutritional status in patients with Parkinson’s disease and its relationship with severity of the disease
Nutrition
Nutrition
Original Research
Original Research
<p style="text-align: justify;"><strong>Background: </strong>Malnutrition, loss of body weight, muscle and fat mass wasting are common in patients with Parkinson's disease, and are associated with disability, longer length of hospital stay, impaired immune system and increased risk of mortality. The aim of this study was to assess the nutritional status in patients with Parkinson's disease and its relation to the severity of the disease.</p>
<p style="text-align: justify;"><strong> Methods:</strong> This cross- sectional study was conducted on 130 patients with Parkinson's disease, with a mean (SD) age of 59.1 (12.9) years in disease stages of 1 to 4. In this study, the Mini Nutritional Assessment (MNA) questionnaire was used along with anthropometric measurements (Body Mass Index (BMI), Mid-arm circumference (MAC), Calf Circumference (CC)) to evaluate the nutritional status, and they were applied by a trained nutritionist. Hoehn and Yahr Scale were used to determine the severity of the disease. One-way ANOVA test was used to assess the relationship between anthropometric indices, nutritional status and severity of disease. Assessment of the relationship between age, duration of disease and nutritional status was categorized according to MNA score, and was performed, using one-way ANOVA. Chi - Square test was utilized to assess the relationship between education level and nutritional status. SPSS Version 18 was used for data analysis.</p>
<p style="text-align: justify;"><strong> Results:</strong> In this study, 30% (n=39) of the participants were diagnosed with normal nutritional status, 58.5% (n=76) were at risk of malnutrition and 11.5% (n=15) were malnourished according to MNA. Reduction of weight, and muscle mass wasting was observed in different disease stages. Muscle mass wasting and worsening nutritional status, based on MNA score, showed a significant increase as the disease progressed, MAC (p=0.009), MNA score (p<0.001). After assessing the relationship between education level, age, duration of disease with nutritional status, the results revealed a significant relationship between age (p=0.008), education level (p<0.001) with nutritional status according to MNA score.</p>
<p style="text-align: justify;"><strong> Conclusion:</strong> Reduction of BMI, depletion of muscle mass, and worsening of nutritional status according to MNA, was observed in many patients along with an increase in the severity of the disease. Assessing nutritional status in those with Parkinson's disease to provide information to identify necessary nutritional intervention is highly recommended.</p>
Nutritional Status, Parkinson’s Disease, Anthropometric Indices, Mini Nutritional Assessment.
1133
1139
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-1088&slc_lang=en&sid=1
Farzad
Shidfar
farzadshidfar@yahoo.com
200319475328460026268
200319475328460026268
No
Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Peivand
Babaii Darabkhani
200319475328460026269
200319475328460026269
No
Iran University of Medical Sciences, Tehran, Iran.
Leila
Yazdanpanah
yazdanpanah_l@yahoo.com
200319475328460026270
200319475328460026270
Yes
Hazrat Rasoul Medical Complex, Iran University of Medical Sciences, Tehran, Iran.
Siamak
Karkheiran
karkheiran.clinic@gmail.com
200319475328460026271
200319475328460026271
No
Movement Disorders Clinic, Hazrat Rasoul Medical Complex, Iran University of Medical Sciences, Tehran, Iran.
Hamid
Noorollahi-Moghaddam
narcist1970@yahoo.com
200319475328460026272
200319475328460026272
No
Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Hamid
Haghani
haghani511@yahoo.com
200319475328460026273
200319475328460026273
No
Department of Biostatistics, School of Management and Information, Iran University of Medical Sciences, Tehran, Iran.