Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1397
11
1
gregorian
2019
2
1
33
1
online
1
fulltext
en
Survival rate of patients with gastric cancer in Hormozgan Province, Iran
Epidemiology
Epidemiology
Original Research
Original Research
<p><strong>Background: </strong>Gastric cancer is the fourth most common form of cancer and the second most common cause of death in the world. It is also one of the most common cancers leading to mortality in Iran. Therefore, this study aimed to determine the survival rate of patients with gastric cancer and its affecting factors in the south of Iran (Hormozgan province).<br>
<strong>Methods: </strong>In this study, all patients with gastric cancer (119 patients) that were diagnosed and registered during 2008 to 2013 in Hormozgan province, were studied. All patients were followed to the end of 2015. Kaplan-Meier method and Cox proportional hazards model were used to draw survival curves and to determine the effective factors on the survival rate of surveyed patients. Moreover, Log-rank test was used to evaluate whether or not survival curves for different groups are statistically equivalent (p<0.05). <br>
<strong>Results: </strong>The mean age of the study population was 58.9±14.91, and most of them were men (72.3% (86 persons)). After diagnosis, the survival rates for 1, 2, 3, 4, and 5 years were 62.2%, 49.4%, 43.7%, 39.7%, and 38% respectively. Survival in men were lower than women, but according to log-rank test this difference was not statistically significant (p=0.325). Also patients with advanced stage cancer had significantly lower survival in comparison to individuals with early stage disease (p<0.001). Based on multiple Cox proportional hazards model, job status of the patients and stage of cancer were effective factors on patients’ survival.<br>
<strong>Conclusion:</strong> Based on the findings of the present study, the survival rate was decreased over time after diagnosis. Stage of a cancer at the time of diagnosis is the most important factor affecting the survival of surveyed patients. This shows that there is a crucial need to diagnos the gastric cancer in early stages.<br>
</p>
Gastric cancer, Survival rate, Kaplan-Meier, Cox proportional hazards model, Log-rank
449
453
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-3174-1&slc_lang=en&sid=1
Maryam
Karimi Jaberi
maryamkarimijaberi@gmail.com
200319475328460062542
200319475328460062542
No
Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
Ali
Gholami
aagholami80@yahoo.com
200319475328460062543
200319475328460062543
No
Noncommunicable Diseases Research Center & Department of Epidemiology and Biostatistics, School of Public Health, Neyshabur University of Medical Sciences, Neyshabur, Iran
Bahman
Cheraghian
maryamkarimijaberi@gmail.com
200319475328460062544
200319475328460062544
No
Department of Internal Medicine, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran
Jamile
Abolghasemi
maryamkarimijaberi@gmail.com
200319475328460062545
200319475328460062545
No
Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
Masoud
Solaymani-dodaran
Masoud.Solaymani-Dodaran@nottingham.ac.uk
200319475328460062546
200319475328460062546
No
Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran
Abdolhossein
Madani
maryamkarimijaberi@gmail.com
200319475328460062547
200319475328460062547
No
Research Center for Social Determinants in Health Promotion, Hormozgan University of Medical Science, Bandar Abbas, Iran
Yaghoob
Ashoori
maryamkarimijaberi@gmail.com
200319475328460062548
200319475328460062548
No
Department of radiation oncology, Omid center, Hormozgan University of Medical Science, Bandar Abbas, Iran
Mehdi
Darabi
maryamkarimijaberi@gmail.com
200319475328460062549
200319475328460062549
No
Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran
Solayman
Moosapoor
maryamkarimijaberi@gmail.com
200319475328460062550
200319475328460062550
No
Vice chancellor of Health, Hormozgan University of Medical Science, Bandar Abbas, Iran
Mohsen
Asadi lari
Mohsen.asadi@yahoo.com
200319475328460062551
200319475328460062551
Yes
Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, & Oncopathology Research Centre, Iran University of Medical Sciences, Tehran, Iran