en Epidemiology Epidemiology Original Research Original Research <p><strong>Background: </strong>Gastric cancer is the fourth most common form of cancer and the second most common cause of death in the world. It is also one of the most common cancers leading to mortality in Iran. Therefore, this study aimed to determine the survival rate of patients with gastric cancer and its affecting factors in the south of Iran (Hormozgan province).<br> &nbsp;&nbsp; <strong>Methods: </strong>In this study, all patients with gastric cancer (119 patients) that were diagnosed and registered during 2008 to 2013 in Hormozgan province, were studied. All patients were followed to the end of 2015. Kaplan-Meier method and Cox proportional hazards model were used to draw survival curves and to determine the effective factors on the survival rate of surveyed patients. Moreover, Log-rank test was used to evaluate whether or not survival curves for different groups are statistically equivalent (p<0.05).&nbsp;<br> &nbsp;&nbsp; <strong>Results: </strong>The mean age of the study population was 58.9&plusmn;14.91, and most of them were men (72.3% (86 persons)). After diagnosis, the survival rates for 1, 2, 3, 4, and 5 years were 62.2%, 49.4%, 43.7%, 39.7%, and 38% respectively. Survival in men were lower than women, but according to log-rank test this difference was not statistically significant (p=0.325). Also patients with advanced stage cancer had significantly lower survival in comparison to individuals with early stage disease (p<0.001). Based on multiple Cox proportional hazards model, job status of the patients and stage of cancer&nbsp;&nbsp; were effective factors on patients&rsquo; survival.<br> &nbsp;&nbsp; <strong>Conclusion:</strong> Based on the findings of the present study, the survival rate was decreased over time after diagnosis. Stage of a cancer at the time of diagnosis is the most important factor affecting the survival of surveyed patients. This shows that there is a crucial need to diagnos the gastric cancer in early stages.<br> &nbsp;</p> Gastric cancer, Survival rate, Kaplan-Meier, Cox proportional hazards model, Log-rank 449 453 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-3174-1&slc_lang=en&sid=1 Maryam Karimi Jaberi maryamkarimijaberi@gmail.com 200319475328460062542 200319475328460062542 No Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Ali Gholami aagholami80@yahoo.com 200319475328460062543 200319475328460062543 No Noncommunicable Diseases Research Center & Department of Epidemiology and Biostatistics, School of Public Health, Neyshabur University of Medical Sciences, Neyshabur, Iran Bahman Cheraghian maryamkarimijaberi@gmail.com 200319475328460062544 200319475328460062544 No Department of Internal Medicine, Faculty of Medicine, Jundishapur University of Medical Sciences, Ahvaz, Iran Jamile Abolghasemi maryamkarimijaberi@gmail.com 200319475328460062545 200319475328460062545 No Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran Masoud Solaymani-dodaran Masoud.Solaymani-Dodaran@nottingham.ac.uk 200319475328460062546 200319475328460062546 No Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran Abdolhossein Madani maryamkarimijaberi@gmail.com 200319475328460062547 200319475328460062547 No Research Center for Social Determinants in Health Promotion, Hormozgan University of Medical Science, Bandar Abbas, Iran Yaghoob Ashoori maryamkarimijaberi@gmail.com 200319475328460062548 200319475328460062548 No Department of radiation oncology, Omid center, Hormozgan University of Medical Science, Bandar Abbas, Iran Mehdi Darabi maryamkarimijaberi@gmail.com 200319475328460062549 200319475328460062549 No Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran Solayman Moosapoor maryamkarimijaberi@gmail.com 200319475328460062550 200319475328460062550 No Vice chancellor of Health, Hormozgan University of Medical Science, Bandar Abbas, Iran Mohsen Asadi lari Mohsen.asadi@yahoo.com 200319475328460062551 200319475328460062551 Yes Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, & Oncopathology Research Centre, Iran University of Medical Sciences, Tehran, Iran