en Medical Education Medical Education Original Research Original Research <div><div></div></div> <strong>Background: </strong>This study aimed to investigate the state of spirituality in the general medicine curricula in Iran.<br> &nbsp;&nbsp; <strong>Methods: </strong>Reference books for general medicine were reviewed and data were analyzed according to the qualitative content analysis method.<br> &nbsp;&nbsp; <strong>Results:</strong> After reviewing references, it was found that only 35 paragraphs of the educational reference pages dealt with this subject. Related topics to spirituality had 2 major themes: (a) spirituality and care (assessment, treatment, palliative care, and bereavement); (b) spirituality and professionalism (considering culture and medical ethics).<br> &nbsp;&nbsp; <strong>Conclusion:</strong> This study showed that despite the importance of the subject and much evidence on spirituality and medicine, medical references have limitations. The authors suggested some strategies to develop a specific course and integrate all educational references with the objectives of the general medical education course in Iran.<br> &nbsp; Spiritual needs, Spiritual health, Medical curriculum, Sociocultural determinant of health, Iran 40 46 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1930-2&slc_lang=en&sid=1 Ruhollah Seddigh sedigh.r@iums.ac.ir 200319475328460063741 200319475328460063741 No Spiritual Health Research Center, Iran University of Medical Sciences, Tehran, Iran Somayeh Azarnik azarniks@gmail.com 200319475328460063742 200319475328460063742 No Spiritual Health Research Center, Iran University of Medical Sciences, Tehran, Iran Nadereh Memaryan memaryan.n@iums.ac.ir 200319475328460063743 200319475328460063743 No Spiritual Health Research Center, & Mental Health Department, School of Behavioral Sciences and Mental Health (Tehran Institute of Psychiatry), Iran University of Medical Sciences, Tehran, Iran Fatemeh Hadi hadi.f@iums.ac.ir 200319475328460063744 200319475328460063744 Yes Mental Health Research Center, Department of Psychiatry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran