en General General Original Research: Clinical Science Original Research: Clinical Science <p style="margin: 0px 0px 10.66px; text-align: justify;"><strong>Background: </strong>Children with mental retardation have various clinical problems. They mostly have motor delay and sensory deficit. Neurorehabilitation focuses on restoring remaining abilities. Thus, the present study was designed to study the effects of simultaneous use of sensory-motor therapy on manual skills of children with mental retardation.<br> &nbsp;&nbsp; <strong>Methods:</strong> In this study, 120 educable boys and girls with mental retardation (9-12 years) were selected from 2 preprimary and primary exceptional centers in Tehran using stratified sampling method considering the geographical dispersion. The participants were divided into 2 equal trial and control groups using simple random sampling. Lincoln-Oseretsky Motor Development Scale, Purdue Pegboard test, and Handwriting Legibility Checklist of Persian Language were used. Simultaneous sensory stimulations and motor exercises were used for 3 one-hour weekly sessions for 12 consecutive weeks. Pre and posttests were done for evaluation. Using parametric paired and independent samples t tests, the findings were analyzed in SPSS 23.<br> &nbsp;&nbsp; <strong>Results:</strong> The manual skills significantly improved following therapeutic use of simultaneous sensory stimulation and motor exercise (p=0.001). In the control group, the pre and post evaluation difference was not significant (p=0.813)<br> &nbsp;&nbsp; <strong>Conclusion: </strong>Based on the findings of this study, simultaneous use of sensory-motor techniques can have better clinical results in the trial group compared to the control group. Thus, these types of techniques should be used more in clinics. However, further studies are needed for more comparison between separate applications of these techniques.<br> &nbsp;<br> &nbsp;</p> Sensory stimulation, Motor exercises, Manual motor skills, Educable mentally Retarded children 914 918 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-4506-1&slc_lang=en&sid=1 Raheleh Mollajani rmollajani@yahoo.com 200319475328460062197 200319475328460062197 No Neuroscience Research Center, Iran University of Medical Sciences, & Institute for Cognitive Science Studies, Tehran, Iran Seyed Saeid Taghavi taghavi.ss@yahoo.com 200319475328460062198 200319475328460062198 No Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran Agha Fatemeh Hosseini f_hosseini@yahoo.com 200319475328460062199 200319475328460062199 No Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran Mona Frahadi monafarhadi@yahoo.com 200319475328460062200 200319475328460062200 No Neuroscience Research Center, Iran University of Medical Sciences, Tehran, & Department of Microbiology, Karaj Branch Islamic Azad University, Karaj, Iran Mana Jameie jameie_mana@yahoo.com 200319475328460062201 200319475328460062201 No Faculty of Medicine, Shaheed Beheshti University of Medical Sciences, & Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran Melika Jameie melika.jameie@gmail.cim 200319475328460062202 200319475328460062202 No Faculty of Medicine, Shaheed Beheshti University of Medical Sciences, & Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran Seyed Behnamedin Jameie jameie.sb@iums.ac.ir 200319475328460062203 200319475328460062203 Yes Department of Medical Basic Sciences, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran