Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1398
11
1
gregorian
2020
2
1
34
1
online
1
fulltext
en
Prevalence and antibiotic resistance of Acinetobacter baumannii among patients in postcardiac surgery intensive care units of Rajaei Hospital, Tehran
Infectious Disease
Infectious Disease
Original Research
Original Research
<strong>Background: </strong>Acinetobacter baumannii is an opportunistic, aerobic, nonfermentative, Gram-negative bacterium that can cause major nosocomial infections, especially in patients hospitalized in intensive care units (ICU). Recently, A. baumannii strains have been resistant to a variety of antibiotics. Thus, it was aimed to evaluate the prevalence of A. baumannii and their resistance to the antibiotics in the patients hospitalized in postcardiac surgery ICU.<br>
<strong> Methods</strong>: This retrospective cross sectional study was performed in Rajaei hospital between March 2014 and February 2016. A. baumannii strains were isolated from blood cultures, catheter cultures, sputum cultures, and wound smear cultures. Then, isolates were characterized using standard morphological, cultural, and biochemical properties according to CLSI 2016. The frequency of A. baumannii species were reported as percent.<br>
<strong> Results</strong>: Among 27 167 patients were admitted to the ICU, 113 individuals, including 55 males and 58 females, were identified as A. baumannii-infected and the prevalence rate was 0.42%. The highest rates of antibiotic sensitivity were related to Meropenem 20 (17.7%) and Colistin 16 (14.1%). The shortest length of stay (LOS) for patients with A. baumannii in the ICU was 3 days, while the longest LOS was 98 days.<br>
<strong> Conclusion</strong>: The findings indicated that A. baumannii strains isolated from postcardiac surgery ICUs had a high prevalence and were sensitive to Meropenem and Colistin. However, new molecular-based techniques are needed to monitor nosocomial infections. Therefore, the treatment of the patients may be feasible by appropriate antibiotic therapy, and infection control policies will be improved by adopting precise disinfection strategies.
Acinetobacter baumannii, Nosocomial infection, Antibiotic, Resistance
28
32
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-5153-1&slc_lang=en&sid=1
Monireh
Kamali
Mklk59@gmail.com
200319475328460063724
200319475328460063724
No
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Shirin
Manshouri
Sh_manshouri@yahoo.com
200319475328460063725
200319475328460063725
No
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Yasser
Bagheri
bagheri_yasser@yahoo.com
200319475328460063726
200319475328460063726
No
Immunology Research Center, Institute of Immunology and infectious Diseases, & Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Masoumeh
Rostami
Rostami@rhc.ac.ir
200319475328460063727
200319475328460063727
No
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Mahdi
Karkhaneh Mahmoudi
مهدی
کارخانه محمودی
Mahdi1457ok@yahoo.com
200319475328460063728
200319475328460063728
No
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Pardis
Moradnezhad
پردیس
مرادنژاد
Moradnezhad.p@iums.ac.ir
200319475328460063729
200319475328460063729
No
Rajaei Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
Farhad
Seif
seif.f@tak.iums.ac.ir
200319475328460063730
200319475328460063730
Yes
Neuroscience Research Center, Iran University of Medical Sciences, & Academic Center for Education, Culture, and Research, Tehran, Iran