Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1397
11
1
gregorian
2019
2
1
33
1
online
1
fulltext
en
MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison
Medical Physics
Medical Physics
Original Research
Original Research
<strong>Background: </strong>Cortical deceleration is the main reason for bone loss at peripheral sites. It was suggested that when peripheral bones were assessed for osteoporosis, management and therapy can be administered early. The main aim of this study was to assess the relationships between the central and peripheral measurements at different skeleton bone sites (spine, femur, forearm, tibia, and calcaneus) with available modalities: DXA, QUS, and MDCT-QCT.<br>
<strong>Methods:</strong> The volunteers recruited in this study did not have any history or evidence of metabolic bone disease. Blood test and DXA measurements were used as inclusion criteria to select 40 healthy participants. The selected volunteers underwent 3 imaging modalities: QCT, DXA, and QUS. DXA-based measurements were made on 3 sites, including spine, femur, and forearm. QCT and QUS measurements were done for distal of tibia and calcaneus bones, respectively. The extracted parameters from the 3 modalities were analyzed using a bivariate (Pearson) correlation (r) in statistical software.<br>
<strong> Results:</strong> The results showed moderate to good correlations between spongy bones in central and peripheral sites from all the modalities. However, there was no correlation between MDCT measures and central bone values. According to correlations between different peripheral sits, aBMD of 33% radius and trabecular vBMD in 38% distal tibia showed weak but significant relationship between peripheral bones (r=-0.342, p=0.044).<br>
<strong>Conclusion:</strong> The findings demonstrated how bones in central and peripheral sites were correlated. Multimodality imaging was used in this group of healthy volunteers. Also, it was found that QCT-based MDCT needs more optimization and requires further investigations. <br>
Multidetector computed tomography, Quantitative computed tomography, Quantitative ultrasound, bone, Normal adult
960
964
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1009-2&slc_lang=en&sid=1
Malakeh
Malekzadeh
mlkm9003@gmail.com
200319475328460062153
200319475328460062153
No
Medical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Mojgan
Asadi
asadim@tums.ac.ir
200319475328460062154
200319475328460062154
No
Osteoporosis Research Center, Endocrinology and Metabolism Clinical Sciences Institute, & Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
Shahrokh
Abbasi-Rad
shahrokh.zita@gmail.com
200319475328460062155
200319475328460062155
No
Quantitative Medical Imaging Systems Group, Research Center for Molecular and Cellular Imaging, & Medical Physics and Biomedical Engineering Department, Tehran University of Medical Sciences, Tehran, Iran
Jamileh
Abolghasemi
abolghasemi1347@yahoo.com
200319475328460062156
200319475328460062156
No
Department of Biostatistics, School of public health, Iran University of Medical Sciences, Tehran, Iran
Zohreh
Hamidi
Zohreh.hamidi@gmail.com
200319475328460062157
200319475328460062157
No
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
Mahsa
Talebi
t.mahsa76@yahoo.com
200319475328460062158
200319475328460062158
No
Quantitative Medical Imaging Systems Group, Research Center for Molecular and Cellular Imaging, & Medical Physics and Biomedical Engineering Department, Tehran University of Medical Sciences, Tehran, Iran
Mohammad Bagher
Shiran
shiran.m@iums.ac.ir
200319475328460062159
200319475328460062159
Yes
Finetech in Medicine Research Center, & Medical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
Hamdireza
Saligheh Rad
h-salighehrad@tums.ac.ir
200319475328460062160
200319475328460062160
No
Quantitative Medical Imaging Systems Group, Research Center for Molecular and Cellular Imaging, & Medical Physics and Biomedical Engineering Department, Tehran University of Medical Sciences, Tehran, Iran