Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1383
6
1
gregorian
2004
9
1
18
2
online
1
fulltext
en
THE PREVALENCE OF ANTIPHOSPHOLIPI D SYNDROME IN PATIENTS WI TH RECURRENT PREGNANCY LOSS: A REPORT FROM SOUTH OF IR AN
Gynecology & Obstetrics
Gynecology & Obstetrics
Original Research: Clinical Science
Original Research: Clinical Science
In order to determine the role of different anti-phospholipid antibodies as an etiologic
factor in recurrent pregnancy failure, a prospective study was done on one-hundred
and thirty-eight women who had unexplained recurrent pregnancy loss (group I)
with one-hundred well-matched women with normal reproductive outcome allocated
as control group (GIl).
Sera from 138 patients and 100 controls were analyzed for anticardiolipin antibody
(ACLA) and lupus anticoagulant (LA). ACLA was measured by Elisa and LA
by activated PTT.
Sixteen women (1l .6%) had positive ACLA in group I, while 3 (3%) of group II
were positive for this antibody (p= 0.0 157 and odds ratio = 4.24).
LA was positive in 12(8.7%) of group I and 3(3%) of group II, but the difference
was not significant (p= 0.074, odds ratio=3.08).
Overall 24 women (17.4%) were positive for one of the mentioned antibodies
(p= 0.00055, OR= 6.81). Four patients were positive for both antibodies.
This study emphasizes the relationship between antiphospholipid syndrome and
recurrent pregnancy failure
Anticardiolipin antibody, lupus anticoagulant, pregnancy loss
119
121
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-87&slc_lang=en&sid=1
J
ZOLGHADRI
20031947532846003560
20031947532846003560
Yes
From the Department of Gynecology and Immunology. Shiraz University of Medical Sciences. Shiraz. Iran.
B
GHARESI-FARD
20031947532846003561
20031947532846003561
No
ME
PARSANEZHAD
20031947532846003562
20031947532846003562
No
S
ALBORZI
20031947532846003563
20031947532846003563
No