Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1383
2
1
gregorian
2004
5
1
18
1
online
1
fulltext
en
COMPARISON OF MORBIDITIES BETWEEN INFANTS OF PREGESTATIONAL & GESTATIONAL DIABETIC MOTHERS
Pediatric
Pediatric
Original Research: Clinical Science
Original Research: Clinical Science
To describe and compare the clinical outcome of infants born to mothers with
gestational and pregestational diabetes mellitus, this study was conducted between January
2000 to January 2002 in Tehran vali-E-- -Asr Hospital. Among 4472 deliveries, we
found 107 infants born to diabetic mothers out of whom 6 were twins.
The prevalence of diabetes in total deliveries was 2.39%. Mean age of gestational
and pregestational diabetic mothers was 30.9 ±5.86 and 31 ± 5.37 respectively.
74 infants (69%) belonged to gestational diabetic mothers. 50% of infants were
male. Mean birth weight of infants was 3067± 784.917 (700 -5600g). Gestational age
in 57% of infants was less than 38 weeks.APGAR score at 1 & 5 minutes was <6 in 10
and 5 cases respectively.
Hypoglycemia was detected in 31 %, hypocalcemia in 13%, hypomagnesemia in
4.5%, polycythemia in 6.8%, macrosomia in 28.6%, small for gestational age in 2%,
respiratory distress syndrome in 8.2%, early sepsis in 9.2%, NICU admission in 23.7%,
and hyperbilirubinemia in 34%.
The incidences of most of these morbidities were higher in infants of pregestational
diabetic mothers. The differences between the incidence of hypoglycemia, hypocalcemia
& 5 minute APGAR score in infants of pre gestational and gestational diabetic
mothers were significant (p<0.05).
There was a significant correlation between the incidence of hypoglycemia and
birth weight of infants (p< 0.05). The existence of congenital anomalies in infants of
gestational diabetic mothers could be due to unrecognized cases of noninsulin dependent
diabetes mellitus, and with respect to mean age of mothers it is advisable to detect
diabetes before pregnancy in high risk groups and correct the level of hemoglobin Alc
before pregnancy. Cleft palate and undescended testes among the anomalies support
this hypothesis that prostaglandin deficiency may have a role in the pathophysiology of
congenital malformations in these infants
Gestational diabetes mellitus, Pregestational diabetes, Infants of diabetic mothers, Neonatal complications.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-105&slc_lang=en&sid=1
FIROUZEH
NILI
20031947532846003611
20031947532846003611
Yes
From the Department a/Pediatrics. Tehran University a/Medical Sciences. Tehran. l.R . Iran
A
MAHDAVIANI
20031947532846003612
20031947532846003612
No