en Pathology Pathology Applicable Applicable <p> <strong> Abstract </strong></p><p>  Malacoplakia is a rare chronic inflammatory disease associated with infection and immunosuppression, and very few occurrences have been reported in the bone. The authors describe the case of a 22-year-old woman with paraplegia and urinary and fecal incontinence whose thoracic spine Magnetic Resonance Imaging suggested a tumoral or extensive inflammatory process in the body of the 8th, 9th and 10th thoracic vertebrae. On histology, however, the area turned out to be malacoplakia of bone. Although microbiologic cultures and polymerase chain reaction were negative for Mycobacterium tuberculosis, the lesion demonstrated regression following treatment with anti-TB regimen which had been started because of clinical suspicion. </p><p>  </p> Malacoplakia of bone, vertebra, rare site 52 54 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1-62&slc_lang=en&sid=1 Mojgan Mokhtari dew_p81@yahoo.com. 20031947532846001574 20031947532846001574 Yes Department of Pathology, Isfahan University of Medical Sciences. Shervin Pejhan 20031947532846001575 20031947532846001575 No Shahid Beheshti University of Medical Sciences. Ahmad Shekarchizadeh 20031947532846001576 20031947532846001576 No Isfahan University of Medical Sciences.