Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1399
10
1
gregorian
2021
1
1
35
1
online
1
fulltext
en
Clinical features of 50 cases of 2019 novel coronavirus in Bandar Abbas, Iran
Infectious Disease
Infectious Disease
Original Research
Original Research
<strong>Background: </strong>There is sparse information to describe the clinical features and outcomes of patients infected with coronavirus disease 2019 (COVID-19).<br>
<strong>Methods: </strong>In a single-center retrospective observational study, 50 patients infected with COVID-19 were studied. Epidemiological, demographic, clinical, laboratory, radiological, and treatment data were collected and analyzed. Outcomes of critically ill patients and noncritically ill patients were compared.<br>
<strong>Results:</strong> The mean age of the patients was 48.8 years, with male predominance. Dry cough, fever, and dyspnea were the most complaining symptoms on admission. Chronic medical illnesses before admission were present in 56% of the patients. The most common laboratory abnormalities were lymphopenia, neutrophilia, thrombocytopenia, increased aspartate aminotransferase, high serum creatinine level, elevated lactate dehydrogenase, and increasing ESR and CRP levels. Bilateral mixed ground-glass opacity and consolidation were observed in chest CT scan of most patients. Some patients required supplemental oxygen and some needed invasive mechanical ventilation. Blood oxygen saturation was different between survivors and nonsurvivors. 10% of patients died, of whom 60% were men. 40% of dead cases had chronic medical illnesses; 60% underwent invasive mechanical ventilation.<br>
<strong>Conclusion:</strong> Among the patients diagnosed with COVID-19 infection, the frequent clinical presentation was with a wide range of signs and symptoms. The laboratory changes suggest that COVID-19 infection may be related to cellular immune deficiency, myocardial, hepatic, and kidney injury. Additional research is needed to elucidate COVID-19 pathogenesis.<br>
SARS-CoV-2, Coronavirus disease 2019, COVID-19, Clinical features, Laboratory, Chest CT scan, Outcomes
50
59
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-6054-1&slc_lang=en&sid=1
Hashem
Jarineshin
hjarineshin@yahoo.com
200319475328460063528
200319475328460063528
No
Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Fateme
Saljoughi
f.saljoughi76@gmail.com
200319475328460063529
200319475328460063529
No
Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Hamideh
Estabraghnia Babaki
h.estabragh@gmail.com
200319475328460063530
200319475328460063530
No
Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Mehdi
Hassaniazad
Mehdihassaniazad@gmail.com
200319475328460063531
200319475328460063531
No
Infectious and Tropical Diseases Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Masoumeh
kheirandish
kheirandishm@yahoo.com
200319475328460063532
200319475328460063532
No
Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Amin
Ghanbarnejad
amin.ghanbarnejad@gmail.com
200319475328460063533
200319475328460063533
No
Social Determinants in Health Promotion Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Shahla
Sohrabipour
sh.sohrabipour@hums.ac.ir
200319475328460063534
200319475328460063534
Yes
Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran