en Pediatric Pediatric Original Research Original Research Although treated properly for epilepsy, a number of epileptic children have intractable seizures and about 5-10 per cent of them do not respond to anti -epileptic drugs. In the years 1986-1996 about 10,000 epileptic patients were treated in the Children's Medical Center in Tehran. A retrospective study of their medical records revealed that 41 of them had intractable seizures. I Of these 41 patients, 56.9% had partial epilepsy, 12.2% grand mal epilepsy, 14 % atypical petit-mal, 7.3% Lennox syndrome, 7.3% infantile spasm and 2.4% myoclonic epilepsy. All of them had received at least two anti-epileptic drugs. 34.1 % were not treated regularly. 31.7% had organic brain dysfunction and 51.6% had behavior disorder (hyperactivity-aggressiveness, etc.). These figures show a lower rate of intractable seizures than that of international statistics. T he most important cause of intractable seizures seems to be irregular treatment of the epilepsy. Epilepsy, Intractable seizures, Irregular treatment. 209 212 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-142&slc_lang=en&sid=1 A A. NASIRIAN 20031947532846003736 20031947532846003736 Yes From the Dept. of Pediatric Neurology, Tehran University of Medical Sciences, Tehran, I.R. Iran.