Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1400
10
1
gregorian
2022
1
1
36
1
online
1
fulltext
en
Response of Growth Hormones and Cortisol to One Session of Moderate-Intensity Endurance Exercise in Patients with Type 2 Diabetes: A Quasi-experimental Study
Endocrinology
Endocrinology
Original Research
Original Research
<strong>Background: </strong>Therapeutic interventions for diabetes are one of the main components of treatment and having proper physical activity in these patients is important from different physical, psychological, and social aspects. The benefits of exercise in these people include improved cardiovascular health and increased self-confidence, contributing to maintaining proper weight, controlling blood pressure, lowering blood lipids, and lowering insulin levels. The objective of this study was to assess the baseline levels of growth hormones and cortisol and the response of these 2 hormones to 1 session of moderate-intensity exercise in type 2 diabetic patients and to compare them with healthy individuals.<br>
<strong>Methods: </strong>This was a quasi-experimental and applied study, with a pretest and posttest design and with 1 control group. Participants included 12 healthy people without diabetes and 12 patients with type 2 diabetes aged over 30 years who were referred to the Diabetes Clinic of Tohid hospital, Kurdistan, Iran. After describing the objectives and hypothesis of the study and the implementation method, informed consent was obtained from all participants. SPSS Version 22 software was used for data analysis and coding. The Shapiro-Wilk normality test was used to assess data distribution. A paired t test, an independent t test, the Wilcoxon test, and the Mann-Whitney U test were used to compare outcomes between the 2 groups before and after the intervention.<br>
<strong>Results: </strong>A total of 24 individuals were included: 5 men and 7 women were included in the diabetic group and 7 men and 5 women were included in the healthy group. The mean duration of diabetes in the diabetic group was 7.82 years. The results showed that there was no reason for rejecting a relationship between 1 session of moderate-intensity exercise and increased growth hormone secretion in healthy individuals (p=0.010), but the relationship between this factor and increased growth hormone secretion in the diabetic participants could be strongly rejected (p=0.900). Also, 1 session of the moderate-intensity exercise was not significantly correlated with cortisol secretion in healthy and diabetic participants (p>0.05).<br>
<strong>Conclusion: </strong>This study revealed that baseline growth hormone levels in healthy participants were higher than those of diabetic participants and 1 session of moderate-intensity exercise significantly increased the growth hormone secretion but did not significantly increase the cortisol secretion.
Type 2 Diabetes, Growth Hormone, Cortisol, Moderate-Intensity Exercise
370
374
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-6212-1&slc_lang=en&sid=1
Adibeh
Yousefi
lotfollahsaed@yahoo.com
200319475328460069483
200319475328460069483
No
Department of Exercise Physiology, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran
Zaher
Etemad
zetemad@iausdj.ac.ir
200319475328460069484
200319475328460069484
Yes
Department of Physical Education, Sanandaj Branch, Islamic Azad University, Sanandaj, Iran
Lotfollah
Saed
lotfollahsaed@yahoo.com
200319475328460069485
200319475328460069485
No
Department of Endocrinology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
Amirhossein
Aliakbar
aliakbar.a@iums.ac.ir
200319475328460069486
200319475328460069486
No
Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
Fatemeh
Soleimany
soleimany.f@iums.ac.ir
200319475328460069487
200319475328460069487
No
Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran