Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1382
5
1
gregorian
2003
8
1
17
2
online
1
fulltext
en
A COMPARATIV E , DOUBLE -BLIND, RANDOMIZE D, PLACEBO- CONTROLLED TRIAL OF INTRAPERITONEAL ADMINISTRATION OF BUPIVACAINE AND LIDOCAINE FOR PAIN CONTROL AFTER DIAGNOSTIC LAPARO SCOPY
Gynecology & Obstetrics
Gynecology & Obstetrics
Original Research
Original Research
The purpose of this study was to compare the effect of intraperitoneal
bupivacaine and lidocaine administration on pain reduction after diagnostic
laparoscopy. In this randomized, double blind, placebo controlled study, diagnostic
laparoscopy was done for one-hundred and ninety-six infertile women with
unexplained infertility. Patients were randomized to 4 groups (A, B,C, and D). At
the end of the procedure, 30 mL of 0.125% bupivacaine, 30 mL of 5% lidocaine
and 30 mL of normal saline was instilled in the pelvic cavity and 15 mL of the
same solution over the diaphragmatic vault in group A, B and C, respectively.
Group D received no intraperitoneal substance. The verbal pain scale questionnaire
was used for assessment of postoperative pain.
In conclusion, when instilled intraperitoneally after diagnostic laparoscopy,
bupivacaine significantly decreases postoperative pain for a long period. It also
reduces the rate of analgesic needed, increases the rate at which patients were
discharged 2 hours after surgery, and decreases hospital stay. It is highly effective
compared to lidocaine and placebo.
Infertility, laparoscopy, pain, bupivacaine, lidocaine.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-157&slc_lang=en&sid=1
ME
PARSANEZHAD
parsame@sums.ac.ir
20031947532846003792
20031947532846003792
Yes
From the Department of Obstetrics & Gynecology, Shiraz University of Medical Sciences
H
VAFAEI
20031947532846003793
20031947532846003793
No
From the Department of Obstetrics & Gynecology, Shiraz University of Medical Sciences
M
LAHSAEE
20031947532846003794
20031947532846003794
No
the Department of Anesthesiology, Shiraz University of Medical Sciences, Shiraz, I.R. Iran
S
ALBORZI
20031947532846003795
20031947532846003795
No
the Department of Anesthesiology, Shiraz University of Medical Sciences, Shiraz, I.R. Iran
EH
SCHMIDT
20031947532846003796
20031947532846003796
No
the Department of Obstetrics & Gynecology, Diakonie Teaching Hospital of Gottingen University, Beremen, Germany.