Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1382
5
1
gregorian
2003
8
1
17
2
online
1
fulltext
en
EPIDEMIOLOGICAL, CLINICAL AND ELECTRODIAGNOSTIC FINDINGS IN CHILDHOOD GUILLAIN-BARRE SYNDROME
Pediatric
Pediatric
Original Research
Original Research
In order to identify the clinical and electrophysiological characteristics of
childhood Guillain-Barre Syndrome (GBS) in East Azarbaijan province, clinical
and electrophysiological data on 40 consecutive children with GBS, admitted to
Tabriz Children's Medical Center from March 21st 1999 to March 20th 2002,
were analyzed. All patients received intravenous immunoglobulin, 400 mg /kg/
day for five consecutive days. They were prospectively followed up for at least 3
months. Analysis of age distribution showed a high occurrence (55%) among
children aged 1- 5 years old. Male patients outnumbered females with a sex ratio
of 1.3: 1. The most frequent antecedent events were upper respiratory tract infections.
The study subjects were subclassified according to electrophysiological data:
52.5% were found to have predominantly acute demyelinating neuropathy, 27.5%
had acute motor axonal neuropathy and in 20% of patients the demyelinating type
of GBS was observed with secondary axonal loss. The disease symptoms were
relatively severe in our patients as only 15% of them were able (with and without
aid) to walk at the peak of their illness. Electrodiagnostic criteria associated with
poor outcome were severe reduction in compound muscle action potential (CMAP)
amplitude and fibrillation potentials (p= 0.034).
Childhood Guillain-Barre syndrome, Epidemiology, Clinical features, Electrodiagnosis, prognosis.
123
127
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-159&slc_lang=en&sid=1
M
BARZEGAR
mm_barzegar@yahoo.com
20031947532846003801
20031947532846003801
Yes
From the Department of Pediatric Neurology, Tabriz Children s Medical Center, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, I.R Iran.
Z
JALALI
20031947532846003802
20031947532846003802
No
V
TOPCHIZADEH
20031947532846003803
20031947532846003803
No