en Pathology Pathology case report case report The authors describe a case of histiocyte-rich B-cell lymphoma (HR-BCL), a variant of diffuse large B-cell lymphoma, in a 51-year-old man. The patient presented with large axillary lymphadenopathy. Histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic CD20 positive B cells. Reactive histiocytes were negative for CD15 and CD30 immunostaining. The final diagnosis was histiocyte-rich B-cell lymphoma (HR-BCL) and the patient was referred to the oncology clinic for treatment. Histocyte - rich B-cell lymphoma, diffuse large B-ce1 l lymphoma 159 161 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-165&slc_lang=en&sid=1 T GHIASI MOGHADDAM 20031947532846003819 20031947532846003819 No From the Department of Pathology, Ghaem Hospital, Mashhad University oj Medical Sciences, Mashhad, I.R. Iran. K GHAFARZADEGAN Kghafarzadegan@hotmail.com 20031947532846003820 20031947532846003820 Yes N SHARIFI 20031947532846003821 20031947532846003821 No