en Nephrology Nephrology Brief Communication Brief Communication The occurrence rate of nephrolithiasis has increased steadily. The development of stone in children depends on certain physicochemical factors. Kidney stones are one of the challenges of pediatric nephrology. We brief reviewed the current literature on the best diagnostic imaging to decrease the complication of nephrolithiasis, and we considered the areas that need future research. Nephrolithiasis, Children, Physicochemical Factors 1175 1177 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-6503-2&slc_lang=en&sid=1 Mohsen Akhavan Sepahi akhavansepahim@yahoo.com 200319475328460090592 200319475328460090592 No Department of Pediatric Nephrology, School of Medicine, & Pediatric Clinical Research of Development Center, Hazrat Masoumeh Hospital, Qom University of Medical Sciences, Qom, Iran Majid Mosavimovahed Moosavimovahed @tums.ac.ir 200319475328460090593 200319475328460090593 Yes 3. Department of Internal Medicine, Nephrology Ward, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran