Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1381
5
1
gregorian
2002
8
1
16
2
online
1
fulltext
en
AUDITORY BRAINSTEM RESPONSES (ABR) IN HYPERBILIRUBINEMIC NEWBORNS
Pediatric
Pediatric
Original Research
Original Research
To evaluate the changes of ABR values in hyperbilirubinemic newborns, 85
cases with severe jaundice (total bilirubin levels over 16 mg/dL and direct bilirubin
less than 2 mg/dL) were selected from those admitted to Children's Medical
Center by simple sampling method. These infants had no other problem except
jaundice. ABR was taken before treatment in all cases and in some (10 cases)
after exchange transfusion or phototherapy as treatment modalities. 41 neonates
(48%) had abnormal ABR values, such as increased hearing threshold, prolonged
latencies of waves I, III & V (p- value<0.05), prolonged interpeak latencies of I-V
& III-V (p-value<0.05), absence of waves and abnormal wave morphology. These
findings could be indicative of both peripheral (8th nerve) and brainstem disturbances.
After treatment ABRs showed improvement in some aspects, such as
latencies of waves I, III & V (p value<0.05), but not in interpeak latencies (I-III,
III -V & I-V) and hearing thresholds. In accordance with previous studies, there
was no association between serum total bilirubin concentration and ABR test
results. This could be interpreted as low significance of serum total bilirubin as a
criterion for early prediction of bilirubin induced encephalopathy.
ABR, Hyperbilirubinemic newborn, Total serum bilirubin
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-209&slc_lang=en&sid=1
M
MOHAMMADI
20031947532846003985
20031947532846003985
Yes
From the Department of Pediatric Neurology, Children s Medical Center, Tehran, I.R. Iran.
MR
ASHRAFI
20031947532846003986
20031947532846003986
No
Assistant Professor
R
SHABANIAN
20031947532846003987
20031947532846003987
No
General Practitioner