en Health Management and Economics Health Management and Economics Original Research Original Research <strong>Background: </strong>The ultimate goal of development from the perspective of human capital development is to have a long, healthy, and creative life. This study aimed to identify the requirements for the effective human resource development in the health system.<br> &nbsp;&nbsp; <strong>Methods:</strong> This mixed method study was performed on 20 managers of Iran&rsquo;s health sector in the qualitative part to reach data saturation in qualitative research. The standard questionnaire of the health system consisting of 15 questions was distributed and collected among 302 managers of the health sector (senior and intermediate managers) and faculty professors who were selected by the stratified random sampling method using the Morgan table. Finally, for data analysis in the quantitative part, confirmatory factor analysis and modeling with partial least squares were used.<br> &nbsp;&nbsp; <strong>Results: </strong>The results showed that 4 of the requirements affecting human resource development were financial requirements with 13 components, service requirements with 14 components, educational requirements with 14 components, and partnership requirements with 7 components.<br> &nbsp;&nbsp; <strong>Conclusion:</strong> According to the results, it is suggested that in order to develop effective human resources in the health system, it is necessary to pay attention to the 4 financial, service, educational, and partnership requirements. Human Resource, Health System, Development 1014 1019 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-7006-1&slc_lang=en&sid=1 Fatemeh Kia mahtabnew5@yahoo.com 200319475328460065802 200319475328460065802 No Fraydoon Rahnamay Rood Poshti rahnama.roodposhti@gmail.com 200319475328460065803 200319475328460065803 Yes Department of Economics, Sciences & Research Branch, Islamic Azad University,Tehran, Iran Farhad Ghafari farhad.ghaffari@yahoo.com 200319475328460065804 200319475328460065804 No Department of Economics, Sciences & Research Branch, Islamic Azad University,Tehran, Iran Seyed Ahmad Hashemi hmd_hashemi@yahoo.com 200319475328460065805 200319475328460065805 No Department of Educational Sciences, Lamerd Branch, Islamic Azad University, Lamerd, Iran Nader Tavakoli tavakoli21651@yahoo.com 200319475328460065806 200319475328460065806 No Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran