en Optometry Optometry Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Pregnancy-induced changes in the physiological responses during the gestational period can affect the eye. This study aimed to evaluate the effect of pregnancy on visual, refractive, vergence, and accommodative status.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> In this cross-sectional study, twenty-five healthy pregnant women with a mean age of 29&plusmn;3.1 were examined. All of the subjects underwent comprehensive ophthalmologic examinations, including anterior segment and fundus examinations and tonometry. Refractive error was determined in each trimester using Autokeratometer. Furthermore, near the point of convergence (NPC), best-corrected visual acuity (BCVA), and near the point of accommodation (NPA) were measured. Data analysis was performed using SPSS version 22. To compare the data during pregnancy, repeated measures analysis of variance (ANOVA) was performed. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> During pregnancy, in the right and left eye, spherical equivalent (SE) had a myopic shift from -0.13 to -0.35 D and +0.096 to -0.23 D, respectively (</span></span><span style="font-size:9.0pt">p</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.049 and </span></span><span style="font-size:9.0pt">p</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.020, respectively). Also, in the right and left eyes BCVA significantly decreased from -0.13 to 0.00 and -0.14 to 0.00 LogMAR, respectively (</span></span><span style="font-size:9.0pt">p</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.039 and </span></span><span style="font-size:9.0pt">p</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.045, respectively). NPA and NPC did not change statistically significantly during pregnancy (</span></span><span style="font-size:9.0pt">p</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.385, and </span></span><span style="font-size:9.0pt">p</span><span style="font-size:9.0pt"><span style="font-style:normal">=0.801, respectively).</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion:</b> Due to the unstable hormonal status, a myopic shift and decrease in BCVA occur during pregnancy. So, any change in their spectacle prescription, fitting of contact lenses, performing refractive surgeries, etc., during this period should be postponed. </span></span></span></span></span></span></span></span> <div></div> Pregnancy, Visual Acuity, Refractive Error, Myopia 765 770 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-7134-1&slc_lang=en&sid=1 Ali Mirzajani mirzajani.a@iums.ac.ir 200319475328460072542 200319475328460072542 No Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Foroozan Narooie-Noori Narooienoori.f@iums.ac.ir 200319475328460072543 200319475328460072543 Yes Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Rasoul Amini vishteh ra.am136@yahoo.com 200319475328460072544 200319475328460072544 No Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Zahra Mirsharif mirsharifzahra@yahoo.com 200319475328460072545 200319475328460072545 No Department of Obstetrics and Gynecology, Gynecology Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Samaneh Azampour azampoursamaneh@yahoo.com 200319475328460072546 200319475328460072546 No Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Hoda Medhat medhat_hoda@yahoo.com 200319475328460072547 200319475328460072547 No Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran Seyyedeh Sara Motahar motaharsara@yahoo.com 200319475328460072548 200319475328460072548 No Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran