Medical Journal of the Islamic Republic Of Iran

en Epidemiology and Outcome of Nontraumatic Lower Limb Amputations Epidemiology Epidemiology Original Research Original Research Background: In order to create a solid evidence base for the development of improved management methods, this study was performed to describe the epidemiology and outcome of nontraumatic lower limb amputations (LLAs).    Methods: This descriptive case series was conducted over a period of 4 years. It included all patients of both sexes and all ages who underwent LLAs for nontraumatic indications.    Results: There were a total of 217 patients with 136 (62.67%) men and 81(37.32%) women. The age range was 7 to 71 years, with a mean of 54.25 ± 11.49 years.  The most common indication for amputation (41.47%) was diabetic foot gangrene. The most common level of amputation (48.29%) was below knee amputation.    Conclusion: Patients with diabetic foot gangrene, malignant tumors, and chronic neuropathic ulcers with osteomyelitis constituted the bulk of the amputees. Diabetes mellitus, obesity, and hypertension were the commonest comorbidities identified among them. Public awareness and education would ensure prompt and early health seeking at the appropriate time and help to prevent the need for major amputations in many instances. The amputees' improved reintegration into society and ability to become contributing members of society would be ensured by the provision of vigorous rehabilitation. Lower Limb Amputations, Lower Extremity Amputation, Complications of Diabetes Mellitus, Peripheral Artery Disease, Deadly Lower Limbs, Diabetic Foot Syndrome 130 138 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-6394-2&slc_lang=en&sid=1 Muhammad Saaiq muhammadsaaiq@apims.net 200319475328460076380 200319475328460076380 Yes National Institute of Rehabilitation Medicine (NIRM), Islamabad, Pakistan