en Medical Genetics Medical Genetics Original Research: Basic Science in Medicine Original Research: Basic Science in Medicine <span style="font-size:14px;"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><b><span style="font-style:normal">Background: </span></b><span style="font-style:normal">People&#39;s knowledge and attitude play a role in deciding whether or not to use assisted reproductive procedures (ART). There is no information about people&#39;s attitudes and awareness about ART in western Iran. Thus, this study was performed to determine the knowledge and attitude of infertile people toward ART.</span></span></span><br> <span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> This cross-sectional study was performed on 124 infertile participants who referred to the in vitro fertilization section of Fatemieh hospital, Hamadan, Iran. To measure the knowledge and attitude of the participants, 2 researcher-made questionnaires were used. Their validity and reliability were confirmed by content validity (eg, content validity index [CVI]; content validity ratio [CVR] ) and the Cronbach alpha, respectively.</span></span></span><br> <span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> The study involved 124 participants, more than half of whom were women (54.8%). The mean of the CVI and the CVR for the attitude questionnaire was 0.76 and 0.79, respectively, and for the knowledge, questionnaire was 0.72 and 0.71, respectively. The Cronbach alpha coefficient obtained for the attitude and knowledge questionnaires was 0.761 and 0.745, respectively. The mean (SD) of the attitude and knowledge of infertile people toward the use of ART was 15.33 &plusmn; 2.91 and 9.04 &plusmn; 2.92, respectively. The study reported that participants&rsquo; age, inhabitation, and job status had a significant effect on their attitude score. Also, the study found that the knowledge score was inversely related to age. The knowledge in those who were unemployed and living in the rural and less than those employed and living in urban areas, respectively.</span></span></span><br> <span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion: </b>The 2 questionnaires designed in this study (knowledge and attitude) have the required validity and reliability. As a result, it appears that increasing people&#39;s knowledge and improving their attitude, particularly among the elderly, is necessary.</span></span></span></span> Assisted Reproductive Techniques, Attitude, Knowledge, Infertility, Reproduction 388 392 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-7287-1&slc_lang=en&sid=1 Niloofar Rabiei niloofarrabiei@yahoo.com 200319475328460069860 200319475328460069860 No Student Research Center, Hamadan University of Medical Sciences, Hamadan, Iran Fatemeh Bahreini f.bahreini2824@gmail.com 200319475328460069861 200319475328460069861 Yes Research Center for Molecular Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Mahnaz Yavangi m_yavangui@yahoo.com 200319475328460069862 200319475328460069862 No Endometrium and Endometriosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran Tayebeh Artimani artimani@umsha.ac.ir 200319475328460069863 200319475328460069863 No Endometrium and Endometriosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran Nooshin Mohammadpour noshinmohammadpour@yahoo.com 200319475328460069864 200319475328460069864 No Endometrium and Endometriosis Research Center, Hamadan University of Medical Sciences, Hamadan, Iran